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Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!)

Henao-Restrepo, A.M.; et al. (2016)
The Lancet. Published Online December 22, 2016 http://dx.doi.org/10.1016/S0140-6736(16)32621-6. Open Access
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Effect of a single inactivated poliovirus vaccine dose on intestinal immunity against poliovirus in children previously given oral vaccine: an open-label, randomised controlled trial

Jacob John, et al. The Lancet (2014)
The Lancet, Early Online Publication, 11 July 2014 doi:10.1016/S0140-6736(14)60934-X *Free registration is required to view this article
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HIV drug resistance surveillance in countries scaling up pre-exposure prophylaxis

World Health Organization WHO (2020) C_WHO
WHO recommends that pre-exposure prophylaxis (PrEP) be offered as an additional prevention choice for HIV-negative individuals at substantial risk of HIV infection as part of combination prevention approaches. HIV drug resistance has been rarely reported among PrEP users who tested HIV positive i... more
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EFFECTIVENESS OF SHORTENED COURSE (≤ 3 DAYS) OF ANTIBIOTICS FOR TREATMENT OF ACUTE OTITIS MEDIA IN CHILDREN

Gulani, A. & Sachdev, H.P.S World Health Organisation (WHO) (2009) C_WHO
A systematic review of randomized controlled efficacy trials | REPORT - DEPARTMENT OF CHILD AND ADOLESCENT HEALTH AND DEVELOPMENT
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The COPSI Manual: Manual for Working with People with Schizophrenia and their Families
recommended

Sangath (2012) CC
The COPSI project is divided into three phases: the first in which the intervention is developed, the second in which researchers evaluate the intervention in a randomised controlled trial, and the final one in which the results of the trial are analysed and disseminated. A COPSI resource kit has ... more
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Effect of Music Intervention on the Behaviour Disorders of Children with Intellectual Disability using Strategies from Applied Behaviour Analysis

Ritu Kalgotra, Jaspal Singh Warwal Disability, CBR & Inclusive Development Journal (DCIDJ) (2017) CC
The effect of music intervention on mild and moderate Intellectually disabled children was studied in non-randomized pre-test post-test control group design at an Indian state (Jammu) J&K
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Special Issue: Newborn Health in Uganda

Kate Kerber, Stefan Peterson & Peter Waiswa Global Health Action (2015)
This special issue on Newborn Health in Global Health Action is being launched to share the experience of how to scale up a cost-effective package of newborn care that involves families, community health workers and health facilities. The results of this community randomized trial, the Uganda Newbor... more
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Cross-sectional Survey to Assess Prevalence of Disability and Access to Services in Albay Province, The Philippines

Hodge, M., Bolinas, A., Jaucian, E., et al. Disability, CBR & Inclusive Development Journal (DCIDJ) (2017) CC
In this article a cluster randomized cross-sectional survey, conducted in Albay Province in the Philippines in April 2016, was used to assess the prevalence of disability and access to support services. This was done with the purpose of generating representative data for local programme development... more
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Adherence interventions and outcomes of tuberculosis treatment: A systematic review and meta-analysis of trials and observational studies

Alipanah N, Jarlsberg L et al. (2018) CC
We systematically reviewed Medline as well as the references of published review articles for relevant studies of adherence to multidrug treatment of both drug-susceptible and drug-resistant TB through February 3, 2018. We included randomized controlled trials (RCTs) as well as prospective and retro... more
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The use of low-cost Android tablets to train community health workers in Mukono, Uganda, in the recognition, treatment and prevention of pneumonia in children under five: a pilot randomised controlled

J.O’Donovan, K. Kabali, C. Taylor, et al. (2018) CC
Human Resources for Health201816:49; https://doi.org/10.1186/s12960-018-0315-7
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Effectiveness and cost-effectiveness of group support psychotherapy delivered by trained lay health workers for depression treatment among people with HIV in Uganda

Nakimuli-Mpungu, E.; S. Musisi, K. Wamala, et al. (2020) CC
: a cluster-randomised trial. Lancet Glob Health 2020; 8: e387–98
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Statement on the use of Dexamethasone for severely ill COVID-19 Patients

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C1
Africa Centers for Disease Control and Prevention (Africa CDC) is aware of the media releases of the preliminary results of a large randomized clinical trial conducted in the United Kingdom, which included dexamethasone, a corticosteroid, as one of the drugs used for the treatment of COVID-19 patien... more
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Communiqué du Centre Africain pour le Contrôle et la Prévention des Maladies (CACM) sur l’utilisation de la dexaméthasone

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C1
Les Centres africains de contrôle et de prévention des maladies (Africa CDC) ont pris connaissance des communiqués de presse concernant les résultats préliminaires d'un vaste essai clinique randomisé mené au Royaume-Uni, qui incluait la dexaméthasone, un corticostéroïde, parmi les médicam... more
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Covid-19 - living NMA initiative

World Health Organization WHO, et al. (2021) C_WHO
As of January 20, 2021 the Covid-19 - living NMA initiative collected 150 RCTs and 36 non-randomised studies of vaccines from the ICTRP. 93 of these trials are recruiting patients.
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Safety and efficacy of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine: an interim analysis of a randomised controlled phase 3 trial in Russia

Logunov, D.Y, et al. (2021) C1
Published:February 02, 2021DOI:https://doi.org/10.1016/S0140-6736(21)00234-8
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WHO Living guideline: Drugs to prevent COVID-19
recommended

World Health Organization WHO (2021) C_WHO
Interim guidance 2 march 2021 Current use of drugs to prevent COVID-19 is variable, reflecting large-scale uncertainty. Numerous randomized trials of many different drugs are underway to inform practice. This first version of the Drugs to prevent COVID-19: A WHO living guideline contains new inform... more
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Testing for Ethnic Discrimination in Outpatient Health Care: Evidence from a Field Experiment in Germany

M. Halla; Kah, C.; Sausgruber, R. Johannes Kepler University Linz (2022) CC
To test for ethnic discrimination in access to outpatient health care services, we carry out an email-correspondence study in Germany. We approach 3,224 physician offices in the 79 largest cities in Germany with fictitious appointment requests and randomized patients’ characteristics. We find t... more
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Routine sterile glove and instrument change at the time of abdominal wound closure to prevent surgical site infection (ChEETAh): a pragmatic, cluster-randomised trial in seven low-income and middle-in

NIHR Global Reserach Health Unit on Global Surgery (2022) CC
The Lancet Vol.400 (2022) p.17-67-1776. Published:October 31, 2022DOI:https://doi.org/10.1016/S0140-6736(22)01884-0. Surgical site infection (SSI) is the most common complication of surgery around the world: ChEETAh trial finds routinely changing gloves and instruments for wound closure could preve... more
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Praziquantel for the treatment of schistosomiasis during human pregnancy

Friedman, J.F. et al. (2018) CC
In 2014, an estimated 40 million women of reproductive age were infected with Schistosoma haematobium, S. japonicum and/or S. mansoni. In both 2003 and 2006, the World Health Organization (WHO) recommended that all schistosome-infected pregnant and breastfeeding women be offered treatment, with praz... more
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Efficacy of single versus four repeated doses of praziquantel against Schistosoma mansoni infection in school-aged children from Côte d'Ivoire based on Kato-Katz and POC-CCA: An open-label, randomised

Hoekstra P.T., Casacuberta-Partal M., van Lieshout L. et al (2020) C2
Preventive chemotherapy with praziquantel (PZQ) is the cornerstone of schistosomiasis control. However, a single dose of PZQ (40 mg/kg) does not cure all infections. Repeated doses of PZQ at short intervals might increase efficacy in terms of cure rate (CR) and intensity reduction rate (IRR). Here, ... more