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WHO advisory committee on variola virus research: report of the twenty-third meeting, virtual meeting, 3-4 November 2021

World Health Organization (WHO) (2021) C_WHO

The Committee discussed the implications for preparedness for smallpox-like events reflected by the ongoing COVID-19 pandemic. The Committee noted how quickly diagnostics and vaccines could be developed and deployed when resources and political will were abundant. This rapidity was also due to the f... more

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Developmental roadmap for antimicrobial susceptibility testing systems

Belkum, A.van, T. T. Bachmann, G. Lüdke, et al. (2019) CC

Nature Reviews Microbiology Vol. 17 (2019)pp.51-62 Antimicrobial susceptibility testing (AST) technologies help to accelerate the initiation of targeted antimicrobial therapy for patients with infections and could potentially extend the lifespan of current narrow- spectrum antimicrobials. Althoug... more

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Epidemiological Alert Mpox (MPXV clade I) - 8 August 2024

World Health Organisation (WHO) (2024) C_WHO

Given the circulation of the variant of clade I of mpox virus (MPXV) in the African Region, which is associated in the African Region with sustained transmission and the occurrence of cases in a wider range of age groups, including children, the Pan American Health Organization/World Health Organiza... more

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Buruli Ulcer: Mycobacterium Ulcerans Disease

Pluschke, G., and K. Röltgen Springer Nature (2017) CC

A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatmen... more

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Эпидемиологический надзор за COVID-19: временные рекомендации, 14 февраля 2022 г.
recommended

World Health Organization WHO (2022) C_WHO

This document summarizes current WHO guidance for public health surveillance of coronavirus disease 2019 (COVID-19) in humans caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). New elements include: update of contact definitions, in line with latest cont... more

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Das Schweizer-Käse-Modell inder Corona Pandemibekämpfung (Video)

Brinkmann, M. (2020) CC

Ihre groesste Stärke entfalten Masken in Kombination mit weiteren Massnahmen. Ein gutes Bild dafür ist das Prinzip von Schweizer-Käse-Scheiben, das der australische Virologe Ian Mackay für das Coronavirus ersonnen hat. Die Löcher symbolisieren die Schlupflöcher für die Viren in den Schutzmass... more

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Trauma, Empowerment und Solidarität

BafF e.V. (2020) CC

Wie passen Trauma und Empowerment zusammen? Was ist den Konzepten gemein und welche Entwicklungen machen sie durch? Wie können komplexe Machtverhältnisse auf individüller und struktureller Ebene beruecksichtigt und überwunden werden? Diese Publikation der Bundesweiten Arbeitsgemeinschaft der Ps... more

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Directrices provisionales de bioseguridad de laboratorio para el manejo y transporte de muestras asociadas al nuevo coronavirus 2019 (2019-nCoV)

OPS OPS (2020) C_WHO

En enero de 2020, el agente etiológico responsable de un grupo de casos de neumonía grave en Wuhan, China, fue identificado como un nuevo betacoronavirus (2019-nCoV), distinto del SARS-CoV y MERS-CoV (1) (2) (3). La secuencia genómica completa de este nuevo agente está disponible y se han desarr... more

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MOOC Malaria

Institut Pasteur (2018) CC

The Institut Pasteur has created a MOOC entirely focused on Malaria, providing a glimpse of the wide range of disciplines involved and questions addressed in malaria research. It goes from basic cell and molecular biology of malaria parasites to field and hosp... more

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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti...ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

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Sequencing of SARS-CoV-2 - first update

European Centre for Disease Prevention and Control ECDC (2021) CC

This technical guidance aims to provide guidelines to laboratories and relevant stakeholders in the European Union (EU), European Economic Area (EEA) and other countries in the WHO European region in making decisions on establishing sequencing capacities and capabilities, in making decisions on whic... more

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Methods for the detection and identification of SARS-CoV-2 variants, March 2021

World Health Organization WHO, Regional Office of Europe (2021) C_WHO

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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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А.12 Что детскому психиатру необходимо знать о генетике

Robert R. Althoff International Association for Child and Adolescent Psychiatry and Allied Professions (2018) C1

Для того чтобы помочь разобраться с детской психиатрической генетикой, мы сначала представим основные концепции общей генетики. Это послужит краткой ознакомител�... more

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Multidrug-resistant tuberculosis in migrants, multi-country cluster - third update, 13 April 2017

European Centre for Disease Prevention and Control (2017) C1

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Enhanced COVID-19 Surveillance at the Community Level in Africa

African Union; Africa CDC Centres for Disease Control and Prevention (2021) CC

The strategy recommends that AU Member States should enhance, where feasible, existing COVID-19 surveillance to include: Community-based surveillance to detect symptomatic cases early for treatment and to avert viral transmission; Sentinel surveillance in high-risk populations to detect ... more

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Diretrizes provisórias de Biossegurança Laboratorial para o Manuseio e Transporte de Amostras Associadas ao Novo Coronavírus 2019

OPASOPS (2020) CC

Entretanto, à luz da possível introdução de um caso suspeito relacionado ao COVID-19 na Região das Américas, a Organização Pan-Americana da Saúde/Organização Mundial da Saúde (OPAS/OMS) recomenda que os Estados-membros garantam sua identificação oportuna, o envio de amostras a laborat�... more

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ECRI-Bericht über Deutschland

ECRI (2019) CC

Die Europäische Kommission gegen Rassismus und Intoleranz (ECRI) wurde vom Europarat ins Leben gerufen. Sie ist ein unabhängiges Gremium, das über die Einhaltung der Menschenrechte wacht, wenn es um die Bekämpfung von Rassismus, Diskriminierung (aufgrund von „Rasse", ethnischer/nationaler Herk... more

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Tip Doc Untersuchung zum Ausschluss von Keimen. Abstrich Gram + MRSA: Nase, Rachen

Bild und Sprache e.V.; Setzer Verlag (2016) C2

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Tip Doc Untersuchung zum Ausschluss von Keimen. Abstrich sog. erweiterter MRSA: Nase, Rachen, Achsel

TipDoc Bild und Sprache e.V.; Setzer Verlag (2016) C2

Эпидемиологический надзор за COVID-19: временные рекомендации, 14 февраля 2022 г. recommended

Эпидемиологический надзор за COVID-19: временные рекомендации, 14 февраля 2022 г.
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