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RTS,S/AS01 malaria vaccine current evidence, including efficacy, safety, feasibility and impact and update on R21/Matrix-M malaria vaccine

Hamel, M.J. World Health Organization WHO (2023) C_WHO
Presentation OPT-SMC malaria vaccine workshop - Jan 2023
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Data requirements and protocol for determining comparative efficacy of vector control products

World Health Organization WHO (2024) C_WHO
The aim of this protocol is to support the conduct of entomological comparative efficacy assessments for vector control products and the associated non-inferiority analysis. This evidence is used to inform discussions within the guidelines developm ... more
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Subregional networks of antimalaria drug efficacy and resistance in Eastern Africa and Horn of Africa countries: meeting report, Kampala, Uganda, 9–10 November 2023

World Health Organization WHO (2025) C_WHO
In November 2022, WHO launched a strategy to address antimalarial drug resistance in Africa, emphasizing the need for stronger surveillance. While regional monitoring networks have been active in other regions, most in Africa have not convened since 2017–2018. To renew collaboration, WHO organized ... more
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An open label, block randomized, community study of the safety and efficacy of coadministered ivermectin, diethylcarbamazine plus albendazole vs. diethylcarbamazine plus albendazole for lymphatic fila

JambulingamI P. , KuttiattI V.S., Krishnamoorthy K. et al (2021) C2
Better drug regimens for mass drug administration (MDA) could accelerate the Global Programme to Eliminate Lymphatic Filariasis (LF). This community study was designed to compare the safety and efficacy of MDA with IDA (ivermectin, diethylcarbamaz ... more
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A systematic map and in-depth review of European telehealth interventions efficacy for chronic obstructive pulmonary disease

Gaveikaite, V.; Grunstrom, C.; Winter, S.; et al. Respiratory Medicine (2019) CC2
The article investigates the effectiveness and challenges of remote monitoring systems for chronic respiratory diseases, focusing on COPD and asthma. It reviews various technologies and their potential to improve patient outcomes through better symptom tracking, medication adherence, and early detec ... more
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Protection from a Single Dose of HPV Vaccine A major public health impact from IARC studies of vaccine efficacy

World Health Organisation (WHO) (2023) C_WHO
Protection from a Single Dose of HPV Vaccine A major public health impact from IARC studies of vaccine efficacy.
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EFFECTIVENESS OF SHORTENED COURSE (≤ 3 DAYS) OF ANTIBIOTICS FOR TREATMENT OF ACUTE OTITIS MEDIA IN CHILDREN

Gulani, A. & Sachdev, H.P.S World Health Organisation (WHO) (2009) C_WHO
A systematic review of randomized controlled efficacy trials | REPORT - DEPARTMENT OF CHILD AND ADOLESCENT HEALTH AND DEVELOPMENT
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Tackling antimalarial drug resistance

World Health Organization WHO (2020) C_WHO
Launch of the WHO Report on antimalarial drug efficacy, resistance and response: 10 years of surveillance (2010–2019). Key findings
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WHO Monographs On Selected Medicinal Plants - Volume 4
recommended

World Health Organization WHO (2009) C_WHO
• provide scientific information on the safety, efficacy, and quality control/ quality assurance of widely used medicinal plants, in order to facilitate their appropriate use in Member States; • provide models to assist Member States in develop ... more
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WHO Monographs On Selected Medicinal Plants - Volume 2

World Health Organization WHO (2007) C_WHO
• provide scientific information on the safety, efficacy, and quality control/ quality assurance of widely used medicinal plants, in order to facilitate their appropriate use in Member States; • provide models to assist Member States in develop ... more
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WHO Monographs On Selected Medicinal Plants - Volume 1

World Health Organization WHO (1999) C_WHO
• provide scientific information on the safety, efficacy, and quality control/ quality assurance of widely used medicinal plants, in order to facilitate their appropriate use in Member States; • provide models to assist Member States in develop ... more
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WHO Monographs On Selected Medicinal Plants - Volume 3

World Health Organization WHO (2007) C_WHO
• provide scientific information on the safety, efficacy, and quality control/ quality assurance of widely used medicinal plants, in order to facilitate their appropriate use in Member States; • provide models to assist Member States in develop ... more
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Guidelines for Pharmacovigilance and Medicine Information System in Rwanda

Ministry of Health, Rwanda (2011) C2
The purpose of these guidelines is to help health workers to participate in the process of continuous surveillance of safety and efficacy of the pharmaceutical products which are used in clinical practice, thus help to achieve the ultimate goal to m ... more
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Decontamination of face masks with steam for mask reuse in fighting the pandemic COVID‐19: experimental supports

Qing‐Xia Ma Hu Shan Chuan‐Mei Zhang; et al. (2020) C2
This experimental study, demonstrated that medical masks and N95 masks remained their blocking efficacy after being steamed on boiling water even for 2 hours, using avian coronavirus of infectious bronchitis virus to mimic SARS-CoV-2. Results demons ... more
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Malaria: Artemisinin partial resistance

World Health Organization WHO (2025) C_WHO
Efficacious antimalarial medicines are critical to malaria control and elimination. Continuous monitoring of their efficacy is needed to inform treatment policies in malaria-endemic countries, and to ensure early detection of, and response to, drug ... more
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World Health Organization Model List of Essential Medicines 24th List
recommended

World Health Organization WHO (2025) C_WHO
Essential medicines are those that satisfy the priority health care needs of a population. They are selected with due regard to disease prevalence and public health relevance, evidence of efficacy and safety and comparative cost-effectiveness. They ... more
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Vaccine Hesitancy in Low- and Middle-income Countries: Potential Implications for the COVID-19 Response

Bhopal,S., and M. Nielsen British Medical Journal (2020) C1
The authors state that researchers, governments and global agencies should proceed with particular care in the evaluation of candidate SARS-CoV-2 vaccines in LMICs, with effective communication to build trust and avoid generation of vaccine hesitancy. Vaccine ... more
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Guidelines for the treatment of human African trypanosomiasis
recommended

World Health Organization World Health Organization WHO (2024) C_WHO
The present guidelines incorporate all these changes, leading to a substantial reconfiguration of therapeutic choices for both disease forms. HAT is a serious, life-threatening disease and the efficacy of fexinidazole depends on swallowing the medi ... more
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South Africa: GUIDELINES FOR THE REGISTRATION OF MEDICINES

Medicines Control Council (MCC), Department of Health Republic of South Africa (2012) C1
This guideline is intended to provide recommendations to applicants wishing to submit applications for the registration of medicines. It represents the Medicines Control Council’s current thinking on the safety, quality and efficacy of medicines. ... more
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Drug Regulation in Kenya

LEAP (2021) CC
Drug registration in Kenya started in 1982; the process mainly involves an evaluation committee at the Kenya Pharmacy and Poisons Board (PPB) that aims to approve products based on quality, safety and efficacy.