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A policy brief highlighting key factors associated with adolescent pregnancy. Adolescent pregnancy undermines girls’ human rights and reduces opportunities to realize their full potential.
Malaria in pregnancy is a significant health problem in malaria-endemic areas. It not only causes substantial childhood morbidity and mortality but
...
also increases the risks of adverse events for pregnant women and their developing fetuses. Most of the burden in these areas is due to infection with Plasmodium falciparum. Artemisinin-based combination therapy (ACT) has been recommended as first-line treatment for uncomplicated P. falciparum malaria in all populations, including pregnant women in their second and third trimesters, since 2006. However, for women in their first trimester of pregnancy, WHO recommended as first-line treatment a combination of quinine and clindamycin.
Based on a review of the evidence conducted in 2022, WHO now recommends artemether–lumefantrine, the ACT with the most human safety data available, as the preferred treatment for uncomplicated P. falciparum malaria in the first trimester of pregnancy. This document presents all relevant evidence on the effects and safety in early pregnancy of artemisinins and partner medicines used in ACTs from both studies in experimental animals and observational studies in humans.
more
Topics in Antiviral Medicine, volume 33 Issue 2 May 2025
Data from the 2011 Ethiopia Demographic and Health Survey
Senegal has adopted the World Health Organization’s (WHO’s) three-pronged strategy for combating malaria in pregnancy (MiP): (1) intermittent preventative treatment
...
in pregnancy (IPTp)1 via directly observed therapy (DOT), (2) distribution and use of insecticidetreated nets (ITNs), and (3) case management of MiP. The country began implementing IPTp in 2003.2 Senegal’s National Malaria Control Program (NMCP) has shown strong leadership in supporting key malaria interventions. 3
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This study aimed to understand the patterns of HIV drug resistance in pregnant women in Mozambique. This might help
...
in tailoring optimal regimens for prevention of mother to child transmission of HIV (pMTCT) and antenatal care.
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Programmatic update
April 2012
Executive Summary
UNAIDS and the World Health Organization have published this updated guidance on ethical considerations in HIV prevention trials. The new guidance is the result of a year-long process that saw more
...
than 80 experts and members of the public give inputs and is published 21 years after the first edition appeared.
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