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HIV-1 drug resistance (HIVDR) genotyping is an essential component of the WHO global HIVDR surveillance strategy. Plasma “gold standard” specimen type for HIVDR genotyping, but its use may not be feasible in rural, remote areas in low- and middle-income countries, since preparing and storing it ... more
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The aim of the operational framework is to ensure 1) accurate collection, handling, shipment and storage of specimens collected in countries implementing HIV drug resistance surveillance; and 2) the availability of quality-assured HIV genotyping laboratory services producing comparable and reliable ... more
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Monitoring HIV drug resistance with CADRE

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CDC leads an international surveillance effort to estimate the occurrence of HIV drug resistance among people with HIV who are taking dolutegravir (DTG)-based treatments. This surveillance effort utilizes Cyclical Acquired HIV Drug Resistance Surveillance (CADRE), a laboratory-based HIV drug resista... more
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National Strategy on HIV Drug Resistance Monitoring and Surveillance in Nepal 2014-2020
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First Bangladesh National Tuberculosis Drug Resistance Survey 2010-2011

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Anti-tuberculosis drug resistance among tuberculosis patients in Ukraine and risk factors for MDR-TB

World Health Organization Europe (2016) C_WHO
Results of the first national survey, 2013–2014
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Report National Tuberculosis Drug Resistance Survey, 2006-2007

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Anti-Tuberculosis drug resistance in the world

World Health Organization; Stop TB Department (2008) C_WHO
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Second nationwide anti-tuberculosis drug resistance survey in Namibia

Ruswa, N.; Mavhunga, F.; J. C. Roscoe; et al. (2019) CC2
Int J Tuberc Lung Dis. 2019 Jul 1;23(7):858–864.Namibia ranks among the 30 high TB burden countries worldwide. Here, we report results of the second nationwide anti-TB drug resistance survey. To assess the prevalence and trends of multidrug-resistant TB (MDR-TB) in Namibia. From 2014 to 2015, pat... more
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Tackling antimalarial drug resistance

World Health Organization WHO (2020) C_WHO
Launch of the WHO Report on antimalarial drug efficacy, resistance and response: 10 years of surveillance (2010–2019). Key findings
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Lenacapavir-associated drug resistance: implications for scaling up long-acting PrEP
recommended

World Health Organization WHO (2025) C_WHO
Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis. Web Annex F
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2025 Update of the Drug Resistance Mutations in HIV-1

Wensing, A.M., V.Calvez, F. Ceccherini-Silberstein, et al. (2025) CC
Topics in Antiviral Medicine, March 4, 2025
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Basics to understand HIV Drug Resistance

Wallis, C. (2023) C1
During ARV drug pressure the HIV-1 RT is able to develop resistance to these drugs by generating mutations
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Pre Exposure Prophylaxis (PrEP) and HIV Drug Resistance

Global Evaluation of Microbicide Sensitivity GEMS (2017) C2
Training materials for healthcare workers
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Subregional networks of antimalaria drug efficacy and resistance in Eastern Africa and Horn of Africa countries: meeting report, Kampala, Uganda, 9–10 November 2023

World Health Organization WHO (2025) C_WHO
In November 2022, WHO launched a strategy to address antimalarial drug resistance in Africa, emphasizing the need for stronger surveillance. While regional monitoring networks have been active in other regions, most in Africa have not convened since 2017–2018. To renew collaboration, WHO organized... more