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Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse. A systematic evidenc ... e map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

Keeping the 100-year-old promise: making insulin access universal

WHO (2021) C_WHO

High prices, hard-to-access human insulin, few insulin producers, and weak health systems are just some of the barriers that people with diabetes face a century after insulin was discovered, WHO notes in a new report

ECDC/EFSA/EMA first joint report on the integrated analysis of the consumption of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from humans and food-producing animals

European Centers for Disease Control and Prevention ECDC (2015) C2

The ECDC, the EFSA and the EMA have for the first time jointly explored associations between consumption of antimicrobials in humans and food-producing animals, and antimicrobial resistance in bacteria from humans and food-producing animals, using 2011 and 2012 data currently available from their re ... more

Zimbabwe: MEDICINES AND ALLIED SUBSTANCES CONTROL ACT

(2001) C2

CHAPTER 15:03 | Acts 14/1969, 62/1971, 35/1974, 20/1978, 41/1978 (s. 35) 39/1979, 7/1987, 11/1988, 18/1989 (s. 27), 1/1996, 6/2000, 22/2001; R.G.N. 899/1978.

Community health worker support to improve HIV treatment outcomes for older children and adolescents in Zimbabwe: a process evaluation of the ZENITH trial

C. D. Chikwari; V. Simms; Joanna Busza; et al. Implementation Science; BMC (2018) CC

Dziva Chikwari et al. Implementation Science (2018) 13:70 https://doi.org/10.1186/s13012-018-0762-5

Clinical Management Rape Survivors Developing Protocols

World Health Organization; UNHCR (2004) C_WHO

Developing protocols for use with refugees and internally displaced persons

Managment of Tuberculosis Training Health Facility Staff. Part A

World Health Organization,et al. (2010) C_WHO

Second Edition

Recommendations for management of common childhood conditions
recommended

World Health Organization (2012)

Evidence for technical update of pocket book recommendations. Newborn conditions, dysentery, pneumonia, oxygen use and delivery, common causes of fever, severe acute malnutrition and supportive care

Integrating severe acute malnutrition into the management of childhood diseases at community level in South Sudan

Emily Keane, Andrea King, Anthony Awira et al. Malaria Consortium South Sudan (2013) C1

Since December 2010, Malaria Consortium has been implementing an innovative approach to community management of severe acute malnutrition, together with an existing integrated community case management (ICCM) programme in South Sudan. This learning paper considers Malaria Consortiums experience of t ... more

Guide pédagogique de l’OMS pour la sécurité des patients

World Health Organisation (WHO) (2011) C_WHO

Le secteur de la santé a beaucoup évolué au cours des 20 dernières années. Les innovations technologiques ainsi que notre connaissance des maladies ont contribué à allonger l’espérance de vie au 20ème siècle. Cependant, l’un des plus grands défis aujourd’hui n’est pas de rester a ... more

Guidelines to reduce stigma Guide 1: What is health-related stigma?

ILEP International Federation of Anti-Leprosy Associations (2011)

Crisis Emergency Risk Communication. Manual
recommended

Centers for Disease Control and Prevention CDC; US Dept. of Health and Human Services (2018) C_CDC

The CERC manual provides an evidence-based framework and recommended practices for anyone who communicates on behalf of an organization responding to major emergencies such as natural disasters.

Healthy Timing and Spacing Of Pregnancy: A Trainer’s Reference Guide
recommended

Extending Service Delivery (ESD) Project, USAID (2010) C1

The Extending Service Delivery (ESD) project has developed Healthy Timing and Spacing of Pregnancy: A Trainer’s Reference Guide as a resource for trainers in developing in-service training for facility-based healthcare providers and community health workers (chws) who already have some basic ex ... more

Shaping our Lives: Learning to Live Safe and Healthy, free from HIV/Syphilis & other STIs

National AIDS Control Organization (NACO), Ministry of Health and Family Welfare, Government of India; Ministry of Rural Development; UNIFEM; et al. (2016) C_WHO

A Booklet on Women and HIV/AIDS for Auxiliary Nurse Midwives (ANMs) Accredited Social Health Activists (ASHAs) Anganwadi Workers (AWWs) and Members of Self-help Groups (SHGs)
Version 2

WASH and the Neglected Tropical Diseases

Ogden, S., Gallo, K., Davis, S., et al Sightsavers, Department for International Development, The International Trachoma Initiative , et al. (2013) C2

A MANUAL FOR WASH IMPLEMENTERS, BOTSWANA Sightsavers | Department for International Development | The International Trachoma Initiative | Children Without Worms | WaterAid | WASH Advocates | Center for Global Safe Water, Emory University | CARE USA

Report on Epilepsy in Latin America and the Caribbean

Pan American Health Organization (PAHOWHO), International League against Epilepsy (ILAE) and International Bureau for Epilepsy (IBE) (2013) C_WHO

Also published in Spanish (2013) with the title: Informe sobre la epilepsia en América Latina y el Caribe - ISBN 978-92-75-31776-1

Inclusion Counts The Economic Case for Disability-Inclusive Development

Banks, L.M. & Keogh, M. Christoffel Blinden Mission (CBM) (2016)

02 - Series on Disability-Inclusive Development

Sustaining Effective Coverage for HIV, Tuberculosis, and Malaria in the Context of Transition in Tanzania

Fleisher, Lisa; Mehtsun, Sinit; Arias, Daniel Results for Development (R4D) (2017) C1

R4D conducted a thorough desk review and qualitative fiscal space analysis, 19 interviews about financing for the three diseases and the extent of alignment between public financial management systems and health policy objectives, and a validation workshop with government officials.
Tanzania’ ... more