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Serious adverse events following treatment of visceral leishmaniasis: A systematic review and meta-analysis

Singh-Phulgenda, S., Dahal, P., Ngu, R. et al. PLOS Neglected Tropical Diseases (2021) C1

Despite a historical association with poor tolerability, a comprehensive review on safety of antileishmanial chemotherapies is lacking. We carried out an update of a previous systematic review of all published clinical trials in visceral leishmaniasis (VL) from 1980 to 2019 to document any reported ... more

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Guidance to facilitate monitoring and evaluation for antimicrobial resistance national action plans

Quadripartite: Food and Agriculture Organization of the United Nations FAO; UN Environment Programme UNEP; World Health Organization WHO; World Organisation for Animal Health WAHO (2023) CC

Antimicrobial resistance (AMR) is a global human, animal, plant and environment health threat that needs to be addressed by every country. The impacts of AMR are wide-ranging in terms of human health, animal health, food security and safety, environmental effects on ecosystems and biodiversity, and ...socioeconomic development. Just like the climate crisis, AMR poses a significant threat to the delivery of the 2030 Agenda for Sustainable Development. The response to the AMR crisis has been spearheaded through the global action plan on antimicrobial resistance (GAP-AMR), developed by the World Health Organization (WHO) in 2015, in close collaboration with the Food and Agriculture Organization of the United Nations (FAO) and the World Organisation for Animal Health (WOAH), and formally endorsed by the three organizations’ governing bodies and by the Political Declaration of the high-level meeting of the United Nations General Assembly on AMR in 2016. In 2022, the three organizations officially became the Quadripartite by welcoming the United Nations Environment Programme (UNEP) into the alliance “to accelerate coordination strategy on human, animal and ecosystem health”. The aim of the GAP-AMR is to ensure the continuity of successful treatment with effective and safe medicines. Its strategic objectives include: • improving the awareness and understanding of AMR; • strengthening the knowledge and evidence base through surveillance and research; • reducing the incidence of infection through effective sanitation, hygiene and infection prevention measures; optimizing the use of antimicrobial medicines in human and animal health; and • developing the economic case for sustainable investment that takes account of the needs of all countries and increasing investment in new medicines, diagnostic tools, vaccines and other interventions. With the adoption of the GAP-AMR, countries agreed to develop national action plans (NAPs) aligned with the GAP-AMR to mainstream AMR interventions nationally. Individually, the Quadripartite took action to advance AMR interventions in their respective sectors. FAO adopted a resolution on AMR recognizing that it poses an increasingly serious threat to public health and sustainable food production, and developed an AMR action plan to support the resolution’s implementation. For its part, WOAH developed a strategy on AMR aligned with the GAP-AMR, acknowledging the importance of a One Health approach to AMR. Similarly, more recently, UNEP’s governing body, the United Nations Environment Assembly, recognized that AMR is a current and increasing threat and a challenge to global health, food security and the sustainable development of all countries, and welcomed the GAP-AMR and the NAPs developed in accordance with its five overarching strategic objectives more

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Drivers, Dynamics and Epidemiology of Antimicrobial Resistance in Animal Production

B.A. Wall, A. Mateus, L. Marshall et al. Food and Agriculture Organization of the United Nations FAO (2016) C2

Antimicrobial resistance (AMR) both in human and veterinary medicine has reached alarming levels in most parts of the world and has now been recognized as a significant emerging threat to global public health and food security. In June 2015, the Food and Agriculture Organization of the United Nati... more

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Assessing the efficiency of rural health centres in Burkina Faso: an application of Data Envelopment Analysis

Marschall P., S.Flessa Journal of Public Health (2010) CC

In this paper we aim to provide information on the importance of efficiency measurement of health care facilities in developing countries. We state that efficiency measurement can be a substantial contribution to saving lives. Therefore we analyse the performance of health centres in rural Burkina F... more

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Target product profiles for animal plasma-derived antivenoms: antivenoms for treatment of snakebite envenoming in sub-Saharan Africa

World Health Organisation (WHO) (2023) C_WHO

This publication describes the first WHO public-benefit Target Product Profiles (TPPs) for snakebite antivenoms. It focuses on antivenoms for treatment of snakebite envenoming in sub-Saharan Africa. Four TPPs are described in the document: Broad spectrum Pan-African polyvalent antivenoms: products ... more

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UNFPA COVID-19 Regional Technical Guidance on Older Persons

United Nations Population Fund UNFPA (2020) C1

This regional technical guidance note was developed for the UNFPA Asia-Pacific Regional Office (APRO) and Asia-Pacific Country Offices to provide guidance on older persons, health workers, and caregivers in the contexts of COVID-19 to effectively support each member state and work with other partner... more

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Pandemic influenza preparedness Framework for the sharing of influenza viruses and access to vaccines and other benefits

World Health Organization WHO (2022) C_WHO

2nd edition . This Framework applies to the sharing of H5N1 and other influenza viruses with human pandemic potential and the sharing of benefits. This Framework does not apply to seasonal influenza viruses or other non-influenza pathogens or biological substances that may be contained in clinical ... more

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India: National Guidelines for HIV Testing

National AIDS Control Organisation (NACO), Ministry of Health & Family Welfare, Government of India (2015) C1

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Alternative drinking-water disinfectants: Bromine, iodine and silver

World Health Organization (WHO) (2018) CC

Disinfection of drinking-water supplies has been one of the most significant public health advancements of the last century with respect to reducing waterborne disease.
Although chlorine has been used as the disinfectant of choice for public drinking-water supplies for the past century, a numbe... more

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Global report on insecticide resistance in malaria vectors: 2010–2016

World Health Organization WHO (2018) C_WHO

As of October 2017, the global database comprised almost 30 000 records, including results from bioassays to measure phenotypic resistance, and biochemical and molecular tests for resistance mechanisms. The current report presents an overview of data on malaria vector resistance for 2010 to 2016. It... more

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The epidemiology of adolescents living with perinatally acquired HIV: A cross-region global cohort analysis

The Collaborative Initiative for Paediatric HIV Education and Research (CIPHER) Global Cohort Collaboration; A. L. Slogrove; M. Schomaker; M.-A. Davies; et al. PLOS Medicine (2018) CC

PLOS Medicine | https://doi.org/10.1371/journal.pmed.1002514 March 1, 2018

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Global Antimicrobial Resistance Surveillance System (GLASS): Molecular methods

World Health Organization WHO (2019) C_WHO

Molecular methods for antimicrobial resistance (AMR)diagnostics to enhance the Global Antimicrobial Resistance Surveillance System

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WHO guidelines on management of Taenia solium neurocysticercosis

World Health Organization WHO (2021) C_WHO

The internationally recognized criteria for diagnosis of neurocysticercosis include a requirement for neuroimaging techniques, such as computerized tomography (CT) and/or magnetic resonance imaging (MRI), ideally supported by serology. These facilities are not available in all settings, especially i... more

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WHO Guidance: Ethics and vector-borne diseases

World Health Organization WHO (2020) C_WHO

The primary audience for this guidance is persons working directly in vector-borne disease prevention and control, including programme managers, researchers and field workers. A brief technical background is provided for the benefit of persons without expertise in vector-borne diseases; readers... more

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Therapeutics for Ebola virus disease
recommended

World Health Organization WHO (2022) C_WHO

The WHO Ebola Virus Disease (EVD) Clinical management: living guidance contains the Organization’s most up-to-date recommendations for the clinical management of people with EVD. Providing guidance that is comprehensive and holistic for the optimal care of patients with EVD throughout their il... more

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ACT-A - Urgent Priorities & Financing Requirements at 10 November 2020

World Health Organization (WHO), The Global Fund, Gavi et al. World Health Organization (WHO) (2020) CC

Six months after its launch on 24 April, the Access to COVID-19 Tools (ACT) Accelerator has already delivered concrete results in speeding up the development of new therapeutics, diagnostics, and vaccines. Now mid-way through the scale-up phase, the tools we need to fundamentally change the course o... more

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Bangladesh: Countdown to 2015 - Maternal, Newborn & Child Survival

Countdown to 2030 Commission (2015) C2

The Countdown country profile presents in one place the best and latest evidence to enable an assessment of a country’s progress in improving reproductive, maternal, newborn, and child health (RMNCH)

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Palliative Care Toolkits and Training Manual
recommended

Worldwide Hospice Palliative Care Alliance (2014) CC

This toolkit has been written to empower health workers in resource-poor settings to integrate palliative care into the work they are doing by grafting the missing elements of care onto what is already in place. The WHPCA, Hospice UK and Palliative Care Works have led this updating of the Palliative... more

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HIV care in Central and Eastern Europe: How close are we to the target?

D. Gokengina,; C. Opreab; J. Begovacc; A. Horban; et al. International Journal of Infectious Diseases; International Society for infectious Diseases ; Elsevier (2018) C2

International Journal of Infectious Diseases 70 (2018) 121–130 https://doi.org/10.1016/j.ijid.2018.03.007 1201-9712/© 2018 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://cr... more

Therapeutics for Ebola virus disease recommended

Palliative Care Toolkits and Training Manual recommended

Therapeutics for Ebola virus disease
recommended

Palliative Care Toolkits and Training Manual
recommended