L’objectif général de la mission est de renforcer le programme national de lutte contre la tuberculose
à travers une assistance technique d’une durée de 12 mois.
La técnica diagnóstica ampliamente usada a nivel mundial corresponde a la Prueba de Tuberculina o test de Mantoux, la que a través de la inyección de antígenos de Micobacterium tuberculosis permite medir la reacción del individuo y estimar su probabilidad de infección. El presente manual tie...ne como objetivo describir la técnica para la realización del examen, además de ofrecer lineamientos para su uso programático en Chile.
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La tuberculosis persiste como una grave problemática para la salud pública a nivel internacional y nacional dado que continúa siendo una de las diez primeras causas de morbilidad y mortalidad derivada de enfermedades infectocontagiosas en la población.
Panam Salud Publica. 2021;45:e22. https://doi.org/10.26633/RPSP.2021.22
The objective of the study was the validation and implementation of GeneXpert MTB/RIF for routine use in the rapid detection of tuberculosis and sensitivity to rifampicin in clinical samples; for this, 1592 respiratory samples were collected and analyzed in the laboratory of Instituto Nacional de In...vestigación en Salud Pública Guayaquil. The analysis of the results of GeneXpert in comparison with smear microscopy showed an initial sensitivity of 99.8% and specificity of 93.2%; The analysis of discrepancies using the results of the culture as a reference method showed that the GeneXpert results considered false negatives turned out to be true negatives, the same happens with the false positives that correspond to true positives. Recalculated the sensitivity and specificity of the GeneXpert was 99.8% and 100% correspondingly. The comparison with the drugs susceptibility test showed a sensitivity of 91.4% and a specificity of 95.5% for the GeneXpert MTB/RIF system. It is concluded that the implementation of the GeneXpert system allows solution to certain problems associated with the application of conventional diagnostic methodologies, decreasing the waiting times, and increasing the sensitivity and specificity in the diagnosis of drug-resistant tuberculosis, thus generating a valuable opportunity for early diagnosis.
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Serie: Documentos Técnico normativos
Herramientas de adaptación del Plan Estratégico Colombia Libre de Tuberculosis post 2015
Convenio 519 de 2015 Colombia, septiembre de 2016
National multi-sectoral strategic plan for tuberculosis control in El Salvador 2017-2021
Guía para el Equpo de Salud
Serie: Documentos Técnico normativos
Public expenditure on TUBERCULOSIS in EL SALVADOR, during the fiscal year 2018