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Document d’information scientifique
24 avril 2020
Le développement d’une immunité face à un agent pathogène à la suite d’une infection naturelle comporte plusieurs étapes et prend généralement une à deux semaines. Une infection virale entraîne immédiatement une réponse immunit
...
aire innée, non spécifique, au cours de laquelle les macrophages, les neutrophiles et les cellules dendritiques ralentissent la progression du virus et peuvent même éviter l’apparition de symptômes. Cette réponse non spécifique est suivie d’une réponse adaptative, au cours de laquelle l’organisme produit des anticorps qui se lient spécifiquement au virus. Ces anticorps sont des protéines appelées immunoglobulines. L’organisme produit également des lymphocytes T qui reconnaissent et éliminent les cellules infectées par le virus. Cette réponse adaptative permet parfois d’éliminer le virus de l’organisme et, si elle est suffisamment forte, d’éviter l’aggravation de la maladie ou la réinfection par le même virus. Ce processus est souvent mesuré par la présence d’anticorps dans le sang.
more
24 апреля 2020 г.
Рекомендации в отношении политики для Европейского региона ВОЗ
В настоящем документе описаны основные факторы, которые государствам-членам реком
...
ндуется
учитывать, принимая решения относительно коррекции масштабных ограничительных мер в области охраны общественного здоровья (таких как, например, ограничение свободы передвижения и повсеместное введение правила о физическом дистанцировании) и одновременного укрепления базового потенциала служб общественного здравоохранения (выявление, изоляция, тестирование и лечение всех пациентов и помещение в карантин всех лиц, с которыми они контактировали), мер личной защиты (гигиена рук и респираторный этикет) и норм личного физического дистанцирования (дистанция между людьми более одного метра). Переходный процесс должен осуществляться с учетом результатов оценки рисков, которую необходимо проводить на национальном, субнациональном и даже районном уровне, поскольку передача инфекции COVID-19
внутри одной и той же страны, как правило, носит неоднородный характер.
more
Entretanto, à luz da possível introdução de um caso suspeito relacionado ao COVID-19 na Região das Américas, a Organização Pan-Americana da Saúde/Organização Mundial da Saúde (OPAS/OMS) recomenda que os Estados-membros garantam sua identificação oportuna, o envio de amostras a laborat
...
rios nacionais ou de referência e a implementação do protocolo de detecção molecular do COVID-19, dependendo da capacidade do laboratório. Até à data, o potencial patogênico e a dinâmica de transmissão do COVID-19 não são completamente claros. Por esta razão e à luz do conhecimento de outros vírus semelhantes (MERS-CoV, SRA-CoV), é necessário manter e reforçar as medidas de biossegurança e os equipamentos de proteção individual para o trabalho com amostras suspeitas de infecção com patógenos respiratórios.
more
O objetivo deste documento é fornecer orientações provisórias de biossegurança laboratorial para testes com amostras clínicas de pacientes que atendam à definição de casos do novo patógeno identificado em Wuhan, China, ou seja, a doença do coronavírus 2019 (COVID-19). A OMS revisará ess
...
as recomendações conforme necessário.
more
Este documento apresenta uma orientação provisória sobre a gestão do fornecimento de sangue em resposta à pandemia da doença causada pelo novo coronavírus (COVID-19). É dirigido a serviços de hemoterapia, autoridades nacionais de saúde, e outros responsáveis pelo fornecimento de sangue e
...
hemoderivados e pela integração do sistema de bancos de sangue com o sistema de saúde pública. A OMS continuará atualizando este documento conforme forem disponibilizadas novas informações.
more
Tips for Engaging Communities during COVID-19 in Low-Resource Settings, Remotely and In-Person
recommended
This brief provides key considerations for engaging communities on COVID-19 and tips for how to engage where there are movement restrictions and physical distancing measures in place, particularly in low-resource settings.
The following checklist can help hospitals assess and improve their preparedness for responding to a community-wide outbreak of COVID-19. Each hospital will need to adapt this checklist to meet its unique needs and circumstances. This checklist should be used as one of several tools for evaluating c
...
urrent plans or in developing a comprehensive COVID-19 preparedness plan.
more
У Плані екстреного реагування з подолання пандемії коронавірусної інфекції covid-19 представлені заходи, які будуть запроваджені гуманітарними організаціям
...
в Україні протягом 2020 року для мінімізації впливу пандемії на здоров’я людей та її опосередкованих соціально-економічних наслідків для добробуту людей у різних сферах життя. З огляду на значні масштаби загрози COVID-19 для населення, заходи реагування будуть здійснюватися по всій Україні, але особлива увага приділятиметься Донецькій і Луганській областям, які потерпають від збройного конфлікту протягом останніх шести років. Так, заплановані заходи реагування на COVID-19 у двох постраждалих областях будуть розглядатись як додаток до поточного Плану гуманітарного реагування для України
more
Laboratory biosafety guidance related to coronavirus disease (COVID-19): Interim guidance, 28 January 2021
recommended
The latest update (28 January 2021) includes the following addition and revision:
biosafety aspects for working with antigen-detecting rapid diagnostic test;
handling new variants of SARS-CoV-2 in the laboratory;
updated assay decontamination before disposal;
personal protectiv
...
e equipment (PPE) for specimen collection;
addressing chemical hazards and their safe disposal; and
the fourth edition of the WHO Laboratory Biosafety Manual (LBM4) is now available and the terminology in this guidance was aligned with the LBM4.
more
Probenmaterial für die PCR-Diagnostik zum direkten Erregernachweis
Verpackung und Versand
Empfehlungen zum Umgang mit Probenmaterial
Direkter Erregernachweis durch RT-PCR
Antikörpernachweise (indirekter Nachweis einer Infektion)
Antigennachweise
Bemerkungen zur Interp
...
retation von Laborergebnissen
Ansprechpartner zu Fragen der Labordiagnostik und Referenzuntersuchungen:
Konsiliarlabor für Coronaviren
Gesellschaft für Virologie
Ständig aktualisiert
Vorgehen bei Patienten mit bestätigter SARS-CoV-2-Infektion
more
Dieser Leitfaden zum Management von COVID-19 Ausbruechen richtet sich in erster Linie an die Fachöffentlichkeit im Gesundheitswesen, insbesondere den ÖGD auf allen Ebenen. Er verweist auf viele bereits existierende generische sowie für COVID-19 entwickelten Dokumente. Diese Empfehlungen sind alle
...
unter www.rki.de/covid-19 zu finden, darunter Empfehlungen für das Kontaktpersonenmanagement, Optionen für die Kontaktreduzierung, Kriterien für die Risiköinschätzung von Grossveranstaltungen und Hilfestellung zum Schutz besonders gefährdeter Gruppen. Informationen für Reisende sind beim Auswärtigen Amt zu finden. Informationen zur regionalen oder lokalen Ebene geben die Landes- und kommunalen Gesundheitsbehörden.
Die Inhalte basieren auf den Erkenntnissen zu Erkrankungen (COVID-19) mit Infektionen durch das neuartige Coronavirus (SARS-CoV-2) zum jeweils angegebenen Datenstand. Das Dokument wird aktualisiert und ergänzt, sobald neue Erkenntnisse eine Aktualisierung/Änderung der Empfehlungen notwendig machen.
more
Empfehlungen des Robert Koch-Instituts für Alten- und Pflegeeinrichtungen und Einrichtungen für Menschen mit Beeinträchtigungen und Behinderungen und für den öffentlichen Gesundheitsdienst
Stand 7.4.2021
Dieser Leitfaden soll ambulant tätige Ärztinnen und Ärzten in der für diese Klärung erforderlichen qualifizierten Gesprächsführung sowie in derkorrespondierenden, krisentauglichen Dokumentation unterstützen. Dazu werden nach einer Vorbemerkung (II.) Hinweise zur Therapiezielklärung (III.),
...
zur Einschätzung der Prognose (IV.) und zur Ermittlung des Patientenwillens (V.) gegeben. Eine Priorisierung (Triage) wegen der Knappheit intensivmedizinischer Ressourcen ist Aufgabe der stationären Intensivmedizin und sollte im ambulanten Bereich vermieden werden (VI.)
more
Nested case-control study of health workers exposed to confirmed COVID-19 patients.
Similar objectives to the cohort study but case-control studies may be cheaper and provide robust evidence to characterize and assess the risk factors for SARS-CoV-2 infection in health workers exposed to COVID-19 p
...
atients.
Health workers with confirmed COVID-19 will be recruited as cases and other health workers in the same health care setting without infection will be recruited as controls (incidence density sampling).
Secondary objectives are similar to the cohort study.
more
Infection preventions
Hygiene
