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Clinical Management of Yellow Fever in the Region of the Americas. Experiences and Recommendations for Health Services

Pan American Health Organisation PAHO (2023) CC
The waves of yellow fever transmission in the Region of the Americas in 2016–2018 involved the largest number of human and epizootic cases to be reported in several decades. Yellow fever is a serious viral hemorrhagic disease that poses a challenge for health professionals. It requires early recog... more
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2019 Antibacterial agents in clinical development: an analysis of the antibacterial clinical development pipeline
recommended

World Health Organization WHO (2019) C_WHO
Of the 50 antibiotics in the pipeline, 32 target WHO priority pathogens but the majority have only limited benefits when compared to existing antibiotics. Two of these are active against the multi-drug resistant Gram-negative bacteria, which are spreading rapidly and require urgent solutions. Gr... more
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Uterotonics for the prevention of postpartum haemorrhage
recommended

World Health Organization WHO (2018) C_WHO
WHO Recommendations 2018 Update The primary audience for these recommendations includes health professionals who are responsible for developing national and local health care guidelines and protocols (particularly those related to PPH prevention and treatment) and those involved in the provision of... more
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From channels to commissioning - a practical guide to epilepsy: lecture notes (Chapter 1 - The incidence and prevalence of epilepsy)

Neligan, A. & Sander, J.W. International League Against Epilepsy (UK Chapter) and Epilepsy Society (2015) CC
This is the fifteenth edition of the lecture notes. They were first published in 1987 as a summary of the material used in the biannual epilepsy teaching weekend organised under the auspices of the UK Chapter of the International League against Epilepsy. (Lecture series consist of a total of 59 cha... more
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Infection Control outside the VHF Treatment Facility

MSF (2008)
This section deals with implementing and improving infection control practices in hospitals, health centres and other health services in the outbreak area. It explains the need for, and implementation of, effective triage procedures, and basic requirements for infection control and supporting activi... more
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Challenges in the diagnosis of asthma in children, what are the solutions? A scoping review of 3 countries in sub Saharan Africa

Magwenzi, P.; Rusakaniko, S.; Sibanda, E.N. et al. Respiratory Research (2022) CC
The article is a scoping review that explores the challenges in diagnosing asthma in children in three sub-Saharan African countries: Nigeria, South Africa, and Uganda. It identifies key barriers, such as a lack of community awareness, inadequate healthcare access, limited diagnostic tools like spir... more
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Guidelines for the management of chronic asthma in adolescents and adults

Lalloo, U.; Wong, M.; Abdool-Gaffar, S. et al. South African Family Practice (2007) CC
Asthma prevalence is increasing worldwide and surveys indicate that the majority of patients in developed and developing countries do not receive optimal care and are therefore not well controlled. The aim of these guidelines is to promote a better standard of treatment based on advances in the unde... more
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A systematic review of historical and current trends in Chagas disease

Álvarez-Hernández D., García-Rodríguez-Arana R., Ortiz-Hernández A. et al. Therapeutic advances in infectious disease (2021) CC
Chagas disease (CD) is caused by Trypanosoma cruzi. When acquired, the disease develops in stages. For diagnosis, laboratory confirmation is required, and an extensive assessment of the patient’s health should be performed. Treatment consists of the administration of trypanocidal drugs, which may... more
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Guidance for country validation of viral hepatitis elimination and path to elimination

World Health Organization WHO (2023) C_WHO
Building on the 2021 Interim guidance, this second version and update, incorporates the lessons and feedback from the hepatitis pilots that successfully demonstrated the feasibility of measuring hepatitis B and C impact targets to demonstrate elimination, whilst highlighting challenges caused by hig... more
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Buruli ulcer : management of Mycobacterium ulcerans disease : a manual for health care providers

J. Buntine; Crofts, K. World Health Organization WHO (2001) CC
This manual is addressed to health care providers dealing with Mycobacterium ulcerans disease (Buruli ulcer). The manual aims to achieve a better understanding of the disease, its clinical presentation and its surgical management. The manual is aimed particularly at district health care providers. A... more
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WHO guidelines on management of Taenia solium neurocysticercosis

World Health Organization WHO (2021) C_WHO
The internationally recognized criteria for diagnosis of neurocysticercosis include a requirement for neuroimaging techniques, such as computerized tomography (CT) and/or magnetic resonance imaging (MRI), ideally supported by serology. These facilities are not available in all settings, especially i... more
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Updated recommendations on first-line and second-line antiretroviral regimens and post-exposure prophylaxis and recommendations on early infant diagnosis of HIV - Interim Guidelines

World Health Organization (WHO) World Health Organization (WHO) (2018) C_WHO
Supplement to the 2016 consolidated Guidelines on the use of antiretroviral drugs for Treating and Preventing HIV infection HIV Treatment
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UNICEF Programme Guidance Document Management of Severe Acute Malnutrition in children: Working towards results at scale

United Nations Children’s Fund UNICEF (2015) C_UNICEF
This Guidance Document provides practical assistance to Country Offices scaling up programmes to manage SAM in young children. It outlines a step-by-step process through which countries can analyse their current situation, identify barriers and bottlenecks through the MoRES approach, and plan action... more
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Guidelines For The Management Of Conditions Specifically Related To Stress

World Health Organization WHO (2013) C_WHO
Objectives and scope of the document This document was developed to provide recommended management strategies for problems and disorders that are specifically related to the occurrence of a major stressful event. The recommended strategies will form the basis of a new module to be added to the WHO ... more
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A practical handbook on the pharmacovigilance of antiretroviral medicines

World Health Organization WHO (2013) C_WHO
This is a detailed manual giving a step by step approach to undertaking the pharmacovigilance of antiretrovirals. It is intended to be a source of practical advice for Pharmacovigilance Centres and health professionals involved in HIV/AIDS prevention and treatment programmes. A number of WHO publica... more
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Guidelines for the management of adult lower respiratory tract infections - Summary

Woodhead M., F. Blasi, S. Ewig, et al. (2011) C2
The guidelines are to be used to guide the management of adults with lower respiratory tract infection (LRTI). As will be seen in the following text, this diagnosis, and the other clinical syndromes within this grouping, can be difficult to make accurately. In the absence of agreed definitions of th... more
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WHO/OIE Manual on Echinococcosis in Humans and Animals: a Public Health Problem of Global Concern

WHOOIE (2001)
This Manual covers all important aspects of echinococcosis, including parasite biology and life-cycles, geographic distribution and prevalence, epidemiology, clinical presentation in humans and animals, diagnosis and treatment, as well as control and prevention using newly developed tools and method... more
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Surgery for victims of war

D. Dufour; S. Kromann Jensen; M.Owen-Smith, et al. ICRC (1998)
This handbook summarizes the experience of leading practitioners in the field of war surgery and is intended to help military and civilian surgical teams treat people wounded in armed conflicts. It covers first aid, admission of urgent cases and triage, skin grafts, treatment of infections, wounds a... more
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Guidelines for Care of Critically Ill Adult Patients with COVID-19 in the Americas. Summary, version 3

Pan American Health Organisation PAHO (2021) C_WHO
This publication provides recommendations for the management of critically ill adult patients with COVID-19 being treated in intensive care units (ICUs) in the Americas. These clinical practice guidelines provide evidence-informed recommendations for identifying markers and mortality risk factors in... more
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Initial clinical management of patients exposed to chemical weapons
recommended

World Health Organization (2014) C_WHO
This interim guidance is aimed at healthcare workers who may receive patients exposed to chemical weapons at their healthcare facilities. It provides questions to guide the identification of contaminated patients, recommendations on personal protection, procedures for decontamin... more