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Treatments for people living with schizophrenia in Sub-Saharan Africa: an adapted realist review

Chidarikire S, Cross M, Skinner I, Cleary M (2018) CC

Int Nurs Rev. 2018 Mar;65(1):78-92. doi: 10.1111/inr.12391. Epub 2017 May 25.

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Ending disease in Africa: control, elimination, and eradication efforts for neglected tropical diseases, scoping review of the literature in the WHO African Region since 1990

World Health Organization WHO (2023) C_WHO

Neglected tropical diseases (NTDs) are a category of chronic, disabling, and at times disfiguring diseases and conditions that occur most commonly in the setting of extreme poverty. Historically, NTDs have received less attention and funding when compared to other diseases occurring in the same regi... more

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Global causes of blindness and distance vision impairment 1990–2020: a systematic review and meta-analysis

Flaxman, S.; Bourne, R.; Sernikoff, S.; et al. The Lancet Global Health (2017) CC

Contemporary data for causes of vision impairment and blindness form an important basis of recommendations in public health policies. Refreshment of the Global Vision Database with recently published data sources permitted modelling of cause of vision loss data from 1990 to 2015, further disaggregat... more

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Diabetes self-management education interventions in the WHO African Region: A scoping review

Kumah, E.; Otchere, G.; Egyakawa Ankomah, S.; et al. PLoS One (2021) CC2

Diabetes mellitus (DM) is one of the commonest chronic diseases worldwide. Self-Management Education (SME) is regarded as a critical element of treatment for all people with diabetes, as well as those at risk of developing the condition. While a great variety of diabetes self-management education (D... more

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The many faces of diabetes. Is there a need for re-classification? A narrative review

Sakran, N.; Graham, Yiitka.; Pintar, T.; et al. BMC Endocrine Disorders Volume 22 Article Number 9 (2022) CC

The alarming rise in the worldwide prevalence of obesity and associated type 2 diabetes mellitus (T2DM) have reached epidemic portions. Diabetes in its many forms and T2DM have different physiological backgrounds and are difficult to classify. Bariatric surgery (BS) is considered the most effective ... more

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Georgia - Report for the National Voluntary Presentation at the ECOSOC 2014 Annual Ministerial Review

The Ministry of Labour, Health and Social Affairs of Georgia (2019) C2

Accessed: 26.09.2019

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Community-Based Interventions for the Prevention and Control of Cutaneous Leishmaniasis: A Systematic Review

Polidano, K., Wenning, B., Ruiz-Cadavid, A. et al. Social Sciences (2022) CC

We reviewed the evidence on community-based interventions for the prevention and control of cutaneous leishmaniasis (CL). Community initiatives tailored towards awareness and mobilisation are regarded as a priority area in the Neglected Tropical Disease Roadmap 2021–2030 by the World Health Organi... more

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Cost-effectiveness of surgery and its policy implications for global health: a systematic review and analysis

Tiffany E Chao; Ketan Sharma; Morgan Mandigo, et al. The Lancet Global Health (2014)

The Lancet Global Health, Volume 2, Issue 6, Pages e334 - e345, June 2014 doi:10.1016/S2214-109X(14)70213-X

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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti...ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

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Challenges in the Management of Bronchial Asthma Among Adults in Nigeria: A Systematic Review

Onyedum, C.C.; Ukwaja, K.N.; Desula, O.O.; Ezeudo, D. (2013) CC2

Asthma is a chronic inflammatory condition characterized by airway hyper-responsiveness to a variety of stimuli largely of allergic origin with reversible airflow limitation. The major clinical features of asthma are wheezing, shortness of breath, and cough. It is a major cause of impaired quality o... more

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How much bilateral and multilateral climate adaptation finance is targeting the health sector? A scoping review of official development assistance data between 2009– 2019

Alcayna T., O’Donnell D., Chandaria S. PLOS Global Public Health (2023) CC

Climate change is adversely affecting human health. Rapid and wide-scale adaptation is urgently needed given the negative impact climate change has across the socio-environmental determinants of health. The mobilisation of climate finance is critical to accelerate adaptation towards a climate resili... more

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Effectiveness of community health worker training programmes for cardiovascular disease management in low-income and middle-income countries: a systematic review

Abdel-All, M; Putica, B.; Praveen, D. et al. BMJ Open (2017) CC

Introduction Community health workers (CHWs) are increasingly being tasked to prevent and manage cardiovascular disease (CVD) and its risk factors in underserved populations in low-income and middle-income countries (LMICs); however, little is known about the required training necessary for them to ... more

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The link between the West African Ebola outbreak and health systems in Guinea, Liberia and Sierra Leone: a systematic review

Haitham Shoman, Emilie Karafillakis and Salman Rawaf (2017) CC

Shoman et al. Globalization and Health (2017) 13:1 DOI 10.1186/s12992-016-0224-2

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Clinical utlity of peptide microarrys in the serodiagnosis of neglected tropical diseases in sub-Saharan Africa: protocol for a diagnostic test accuracy sytematic review

Vengesai A., Naicker T., Kasambala M., et al. (2021) C2

BMJ Open 2021;11:e042279. doi:10.1136/bmjopen-2020-042279. Neglected tropical diseases tend to cluster in the same poor populations, and to make progress with their control, they will have to be dealt with in an integrated manner. Peptide microarrays may be a solution to tese problems, where diagnos... more

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Combined Use of Delamanid and Bedaquiline to Treat Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis: A Systematic Review

G. B. Migliori, E. Pontali, G. Sotgiu, et al. International Journal of Molecular Scienes (2017) C2

Int. J. Mol. Sci. 2017, 18, 341, 1 - 10

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Task-sharing interventions for improving control of diabetes in low-income and middle-income countries: a systematic review and meta-analysis

Linju Maria, J.; et al. (2020) CC

Lancet Glob Health 2020Published OnlineNovember 27, 2020 https://doi.org/10.1016/S2214-109X(20)30449-6

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Infrastructure, policy and regulatory interventions to increase physical activity to prevent cardiovascular diseases and diabetes: a systematic review

Durão, S.; Burns, J.; Schmidt, B. et al. BMC Public Health (2023) CC

Background Noncommunicable diseases are major contributors to morbidity and mortality worldwide. Modifying the risk factors for these conditions, such as physical inactivity, is thus essential. Addressing the context or circumstances in which physical activity occurs may promote physical activity a...t a population level. We assessed the effects of infrastructure, policy or regulatory interventions for increasing physical activity. Methods We searched PubMed, Embase and clinicaltrials.gov to identify randomised controlled trials (RCTs), controlled before-after (CBAs) studies, and interrupted time series (ITS) studies assessing population-level infrastructure or policy and regulatory interventions to increase physical activity. We were interested in the effects of these interventions on physical activity, body weight and related measures, blood pressure, and CVD and type 2 diabetes morbidity and mortality, and on other secondary outcomes. Screening and data extraction was done in duplicate, with risk of bias was using an adapted Cochrane risk of bias tool. Due to high levels of heterogeneity, we synthesised the evidence based on effect direction. Results We included 33 studies, mostly conducted in high-income countries. Of these, 13 assessed infrastructure changes to green or other spaces to promote physical activity and 18 infrastructure changes to promote active transport. The effects of identified interventions on physical activity, body weight and blood pressure varied across studies (very low certainty evidence); thus, we remain very uncertain about the effects of these interventions. Two studies assessed the effects of policy and regulatory interventions; one provided free access to physical activity facilities and showed that it may have beneficial effects on physical activity (low certainty evidence). The other provided free bus travel for youth, with intervention effects varying across studies (very low certainty evidence). Conclusions Evidence from 33 studies assessing infrastructure, policy and regulatory interventions for increasing physical activity showed varying results. The certainty of the evidence was mostly very low, due to study designs included and inconsistent findings between studies. Despite this drawback, the evidence indicates that providing access to physical activity facilities may be beneficial; however this finding is based on only one study. Implementation of these interventions requires full consideration of contextual factors, especially in low resource settings. more