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Clinical and public health implications of acute and early HIV detection and treatment: a scoping review

Rutstein, S.E., J. Ananworanich, S. Fidler, et al. Journal of the International AIDS Society (2017) CC

Rutstein SE et al. Journal of the International AIDS Society 2017, 20:21579 http://www.jiasociety.org/index.php/jias/article/view/21579 | http://dx.doi.org/10.7448/IAS.20.1.21579

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Infrastructure, policy and regulatory interventions to increase physical activity to prevent cardiovascular diseases and diabetes: a systematic review

Durão, S.; Burns, J.; Schmidt, B. et al. BMC Public Health (2023) CC

Background Noncommunicable diseases are major contributors to morbidity and mortality worldwide. Modifying the risk factors for these conditions, such as physical inactivity, is thus essential. Addressing the context or circumstances in which physical activity occurs may promote physical activity a...t a population level. We assessed the effects of infrastructure, policy or regulatory interventions for increasing physical activity. Methods We searched PubMed, Embase and clinicaltrials.gov to identify randomised controlled trials (RCTs), controlled before-after (CBAs) studies, and interrupted time series (ITS) studies assessing population-level infrastructure or policy and regulatory interventions to increase physical activity. We were interested in the effects of these interventions on physical activity, body weight and related measures, blood pressure, and CVD and type 2 diabetes morbidity and mortality, and on other secondary outcomes. Screening and data extraction was done in duplicate, with risk of bias was using an adapted Cochrane risk of bias tool. Due to high levels of heterogeneity, we synthesised the evidence based on effect direction. Results We included 33 studies, mostly conducted in high-income countries. Of these, 13 assessed infrastructure changes to green or other spaces to promote physical activity and 18 infrastructure changes to promote active transport. The effects of identified interventions on physical activity, body weight and blood pressure varied across studies (very low certainty evidence); thus, we remain very uncertain about the effects of these interventions. Two studies assessed the effects of policy and regulatory interventions; one provided free access to physical activity facilities and showed that it may have beneficial effects on physical activity (low certainty evidence). The other provided free bus travel for youth, with intervention effects varying across studies (very low certainty evidence). Conclusions Evidence from 33 studies assessing infrastructure, policy and regulatory interventions for increasing physical activity showed varying results. The certainty of the evidence was mostly very low, due to study designs included and inconsistent findings between studies. Despite this drawback, the evidence indicates that providing access to physical activity facilities may be beneficial; however this finding is based on only one study. Implementation of these interventions requires full consideration of contextual factors, especially in low resource settings. more

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Impact of COVID-19 on the indigenous population of Brazil: a geo-epidemiological study

Alves J.D., Abade A.S., Peres W.P. et al. Cambridge University Press (2021) CC

This study aimed to analyze the geographical distribution of coronavirus disease 2019 (COVID-19) and to identify high-risk areas in space and time for the occurrence of cases and deaths in the indigenous population of Brazil. This is an ecological study carried out between 24 March and 26 October 20... more

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The contribution of female community health volunteers (FCHVs) to maternity care in Nepal: a qualitative study

Panday, S., P. Bissell , E.van Teijlingen, et al. (2017) CC

BMC Health Services Research (2017) 17:623 DOI 10.1186/s12913-017-2567-7

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Antimicrobial resistance in Africa: a systematic review

Tilahun Tadesse, B., E. A. Ashley, S. Ongarello et al. BMC Infectious Diseases (2017) C2

Internationally, there is a growing concern over antimicro-bial resistance (AMR) which is currently estimated to ac-count for more than 700,000 deaths per year worldwide. If no appropriate measures are taken to halt its pro-gress, AMR will cost approximately 10 million lives andabout US$100 trillion... more

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Challenges in the diagnosis of asthma in children, what are the solutions? A scoping review of 3 countries in sub Saharan Africa

Magwenzi, P.; Rusakaniko, S.; Sibanda, E.N. et al. Respiratory Research (2022) CC

The article is a scoping review that explores the challenges in diagnosing asthma in children in three sub-Saharan African countries: Nigeria, South Africa, and Uganda. It identifies key barriers, such as a lack of community awareness, inadequate healthcare access, limited diagnostic tools like spir... more

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Ancient pathogens provide a window into health and well-being

Lewis, C. Jr., Akinyi, M., DeWitte, S. et al. Proceedings of the National Academy of Sciences PNAS (2022) CC

This perspective draws on the record of ancient pathogengenomes and microbiomes illuminating patterns of infectious disease over the course of the Holocene in order toaddress the following question. How did major changes inliving circumstances involving the transition to and intensification of farmi... more

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The Chagas disease study landscape: A systematic review of clinical and observational antiparasitic treatment studies to assess the potential for establishing an individual participant-level data plat

Maguire, B.J.; Dahal, P.; Rashan, S. et al. PLOS Neglected Tropical Diseases (2021) CC

Chagas disease (CD), caused by the parasite Trypanosoma cruzi, affects ~6–7 million people worldwide. Significant limitations still exist in our understanding of CD. Harnessing individual participant data (IPD) from studies could support more in-depth analyses to address the many outstanding resea... more

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The Chagas disease study landscape: A systematic review of clinical and observational antiparasitic treatment studies

Maguire, B.; Dahal, P.; Rashan, S.; et al. (2021) CC

PLoS Neglected Tropical diseases August 16, 2021 https://doi.org/10.1371/journal.pntd.0009697 Chagas disease, also known as American trypanosomiasis, is a neglected tropical disease transmitted by triatomine insects, first identified in 1909. Chagas disease affects approximately 6–7 million peop... more

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Modelling interventions to control COVID-19 outbreaks in a refugee camp

Gilman, R.T.; S. Mahroof-Shaffi, C. Harkensee, A.T Chamberlain (2020) CC

BMJ Global Health, Vol.5 No. 12Spatial subdivision of the camp (‘sectoring’) was able to ‘flatten the curve’, reducing peak infection by up to 70% and delaying peak infection by up to several months. The use of face masks coupled with the efficient isolation of infected individuals reduced t... more

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Capacity-building for a strong public health nutrition workforce in low- resource countries

Delisle, H.; Shrimpton, R.; Blaney, S. et al. Bulletin of the World Health Organization (2017) C_WHO

The document addresses the pressing issues of global malnutrition and the urgent need to build workforce capacity in public health nutrition, particularly in low- and middle-income countries. It highlights the dual burden of malnutrition, characterized by the coexistence of undernutrition and overnu... more

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Management of chronic obstructive pulmonary disease—A position statement of the South African Thoracic Society: 2019 update

Abdool-Gaffar, M. S.; Calligaro, G.; Wong, M.L. et al. Journal of Thoracic Disease (2019) CC2

The document outlines the 2019 update to the South African guideline for managing chronic obstructive pulmonary disease (COPD). It emphasizes the importance of early diagnosis, prevention through smoking cessation, use of bronchodilators as primary pharmacotherapy, and a comprehensive approach to pa... more

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The Child and the liberation from the shadow of the terrible big fear. A Trauma-Picture-Book about Help for Parents und their Child

Stein, S. (2017) C2

The Child and the liberation from the shadow of the terrible big fear Дитина і звільнення від тіні її надзвичайно великого страху Trauma Bilderbuch Ілюстрована книга

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Molecular and Clinical Aspects of Chronic Manifestations in Chagas Disease: A State-of-the-Art Review - ProQuest

Medina-Rincón G.J., Gallo-Bernal S., Jiménez P.A. et al Pathogens (2021) C2

Chronic manifestations of Chagas disease present as disabling and life-threatening conditions affecting mainly the cardiovascular and gastrointestinal systems. Although meaningful research has outlined the different molecular mechanisms underlying Trypanosoma cruzi’s infection and the host-parasit... more

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Integration of Water, Sanitation, and Hygiene for the Prevention and Control of Neglected Tropical Diseases: A Rationale for Inter-Sectoral Collaboration

Freeman, M.C.; Ogden, S.; Jacobson, J. et al PLoS Neglected Tropical Diseases (2013) C2

South Sudan has a high burden – among the highest in sub-Saharan Africa – of neglected tropical diseases (NTDs). This adversely affects the health and social and economic well-being of people in the country. The prevention, control and eventual elimination of many NTDs depend heavily on improved... more

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The Chagas disease study landscape: A systematic review of clinical and observational antiparasitic treatment studies to assess the potential for establishing an individual participant-level

Maguire, B.; Dahal, P.; Rashan, S. et al. PLoS Neglected Tropical diseases (2021) CC

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Building Research and Development Capacity for Neglected Tropical Diseases Impacting Leishmaniasis in the Middle East and North Africa: A Case Study

Rafati, S.; Kamhawi, S.; Valentuela, J.; Ghanei, M. PLoS Neglected Tropical diseases (2015) CC

There is an urgent need to build Research and Development (R&D) capacity for leishmaniasis and other neglected tropical diseases (NTDs) in the Middle East and North Africa. The neglected tropical diseases are a group of 17 viral, bacterial, protozoan, and helminthic infections that often have high m... more

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Healthcare Workers’ Knowledge about Chagas Disease: A Systematic Review

Monteiro Soares Cajaiba-Soares, A.; M.S. Martinez-Silveira, D. Lopes Paim Miranda,et al. (2021) C2

Transmission of Chagas disease (CD) has decreased in recent decades, but the disease remains an important problem in endemic areas. There was an increase in the proportion of nonvector transmission, mainly in nonendemic countries. The aim of this study was to gather evidence concerning healthcare pr... more

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Health workforce governance for compassionate and respectful care: a framework for research, policy and practice

Cometto, G.; S. Assegid; G. Abiyu, et al. (2022) C1

BMJ Global Health 2022;7:e008007. doi:10.1136/ bmjgh-2021-00800

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COVID-19 in Yemen: preparedness measures in a fragile state

Dureab, F.; S. Al-Awlaqi and A.Jahn The Lancet (2020) CC

The Lancet DOI: 10.1016/S2468-2667(20)30101-8 WHO declared COVID-19 to be a pandemic on March 11, 2020. The pandemic eventually reached Yemen, with the first laboratory confirmed case announced on April 10. emen has structural vulnerabilities that have developed over a protracted period of conflic... more