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The lack of an African research ethics framework during epidemic emergencies (EE) has been a glaring concern
amongst African scholars for decades. In the context of major public health emergencies of continental and global health concern over the last five years, such as Ebola in 2019, COVID in 202
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0 and Mpox in 2024, and ongoing epidemics, including those of pandemic potential, the need for such a framework is evident. Ethics frameworks for research during emergencies have been published (World Health Organisation, 2016; Nuffield Council on Bioethics, 2020). However, there is currently no African and continent-wide, coherent guidance that promotes African values, elaborated by Africans for hosting research during EE on the continent. To address this gap, the African Centre for Disease Control convened an Ethics Working Group (Ethics WG) to develop an African
framework that embraces dominant African principles/values that might guide the ethical conduct of research in
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Between April 2018 and November 2020, the Democratic Republic of Congo (DRC) experienced its 11th Ebola virus disease (EVD) outbreak. Tanzania’s cross-border interactions with DRC through regular visitors, traders, and refugees are of concern, given the potential for further spread to neighboring
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countries. This study aimed to estimate the risk of introducing EVD to Tanzania from DRC. National data for flights, boats, and car transport schedules from DRC to Tanzania covering the period of May 2018 to June 2019 were analyzed to describe population movement via land, port, and air travel and coupled with available surveillance data to model the risk of EVD entry. The land border crossing was considered the most frequently used means of travel and the most likely pathway of introducing EVD from DRC to Tanzania. High probabilities of introducing EVD from DRC to Tanzania through the assessed pathways were associated with the viability of the pathogen and low detection capacity at the ports of entry. This study provides important information regarding the elements contributing to the risk associated with the introduction of EBV in Tanzania. It also indicates that infected humans arriving via land are the most likely pathway of EBV entry, and therefore, mitigation strategies including land border surveillance should be strengthened.
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