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Born too soon: the global action report on preterm birth

World Health Organization; March of Dimes; The Partnership for Maternal, Newborn & Child Health; Save the Children WHO (2012)
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Guidance on oral pre-exposure prophylaxis (PrEP) for serodiscordant couples, men and transgender women who have sex with men at high risk of HIV: recommendations for use in the context of demonstratio

World Health Organization (2012)
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Global Measles and Rubella Strategic Plan 2012-2020

World Health Organization WHO; Measles Initiative (2012) C_WHO
This ten year global plan for measles and rubella outlines the strategy that needs to be fully implemented to achieve the measles and rubella goals endorsed by the World Health Assembly. The plan sets out the: vision, goals and targets for the 2011-2020 period, recommended strategies, guiding princi... more
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Guideline: Vitamin D supplementation in pregnant women

World Health Organization (WHO) (2012) C_WHO
Vitamin D deficiency is thought to be common among pregnant women, particularly during the winter months, and has been found to be associated with an increased risk of pre-eclampsia, gestational diabetes mellitus, preterm birth, and other tissue-specific conditions. This guideline is intended for ... more
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Antidepressants (Tricyclic Antidepressants and Selective Serotonin Reuptake Inhibitors) in treatment of adults with depression

World Health Organization WHO (2012) C_WHO
Q 1: Are antidepressants (Tricyclic Antidepressants (TCA) and Selective Serotonin Reuptake Inhibitors (SSRI)) better (more effective than/as safe as) than treatment as usual (placebo) in adults with depressive episode/disorder?
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Role of anticholinergic medications in patients requiring long-term antipsychotic treatment for psychotic disorders

World Health Organization WHO (2012) C_WHO
Q6: In individuals with psychotic disorders (including schizophrenia) who require long term antipsychotic treatment, are anticholinergic medications more effective in preventing or reducing extrapyramidal side-effects and/or improving treatment adherence than placebo/treatment as usual?
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Physical Activity

World Health Organization WHO (2012) C_WHO
Q6: Is advice on physical activity better (more effective than/as safe as) than treatment as usual in adults with depressive episode/disorder with inactive lifestyles
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Pharmacological and nonpharmacological interventions for children with attention-deficit hyperactivity disorder (ADHD)

World Health Organization (2012) C_WHO
Q7: What is the effectiveness, safety and role of pharmacological and non-pharmacological interventions, within non- specialist health care for children with a diagnosis of Attention-deficit hyperactivity disorder (ADHD)?
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The global doctor

Willott C et al. UCL Institute for Global Health and Development Education Research Centre, Institute of Education (2012) C2
This report explores the reasons why global health is critical to medicine and what this means for medical education. It argues that an understanding of global health is important for all students and practicing doctors, rather than being an ‘add-on’ or ‘option’ for specialization.
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Treatment of psychostimulant dependence

World Health Organization (2012) C_WHO
Q3: Are pharmacotherapies safe and effective for the treatment of psychostimulant dependence (maintenance or relapse prevention) in non-specialized settings?
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Brief psychosocial interventions

World Health Organization (2012) C_WHO
Q1: Are brief psychosocial interventions for people using cannabis or psychostimulants effective in reducing drug use, dependence and harm from drug use?
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When to discontinue antiepileptic drug treatment in adults and children

World Health Organization WHO (2012) C_WHO
Q9. In adults and children with convulsive epilepsy in remission, when should treatment be discontinued?
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Management of febrile seizures

World Health Organization WHO (2012) C_WHO
Q3: Can febrile seizures (simple or complex) be managed at first or second level care by non-specialist health care providers in low and middle income country settings? What is the role of diagnostic tests in the management of febrile seizures by non-specialists in low and middle income settings? Fo... more
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Role of EEG in management of convulsive epilepsy

World Health Organization WHO (2012) C_WHO
Q5: What is the added advantage of doing an electroencephalography (EEG) in people with convulsive epilepsy in non- specialist settings in low and middle income countries?
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Interventions for carers of people with dementia

World Health Organization (2012) C_WHO
Q9: For carers of people with dementia, do interventions (psychoeducational, cognitive-behavioural therapy counseling/case management, general support, training of caregivers, multi-component interventions and miscellaneous interventions) when compared to placebo/comparator, produce benefits/harm in... more
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Role of a medical review

World Health Organization (2012) C_WHO
Q8: For people with dementia, what is the role of a medical review (including comorbid physical and mental conditions and medication use)?
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Conventional and and atypical antipsychotics & antidepressant (trazodone) for behavioural and psychological symptoms in people with dementia

World Health Organization (2012) C_WHO
Q3: For behavioural and psychological symptoms in people with dementia, do following drugs, when compared to placebo/comparator, produce benefits/harm in the specified outcomes?
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Role of neuroimaging in management of convulsive epilepsy

World Health Organization WHO (2012) C_WHO
Q6: What is the added advantage of doing neuroimaging in people with convulsive epilepsy in non-specialist settings in low and middle income countries?
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Management of epilepsy in women of child bearing age

World Health Organization (2012) C_WHO
Q11: 11a). In women with epilepsy, should antiepileptic therapy be prescribed as monotherapy or polytherapy to decrease the risk of fetal malformations? 11b). Does the use of folic acid preconceptually decrease the risk of foetal malformations in women with epilepsy? 11c). Do phenytoin, phenobarbi... more
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Duration of antidepressant treatment

World Health Organization WHO (2012) C_WHO
Q 2: How long should treatment with antidepressants continue in adults with depressive episode/disorder?