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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Guidelines for antiretroviral therapy in Ghana

Ghana AIDS Commission (2010) C1

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African Union AMR Landmark Report: Voicing African Priorities on the Active Pandemic

Africa Center for Disease Control and Prevention (2024) CC

Antimicrobial resistance (AMR) has emerged as a leading cause of death in the African region, surpassing fatalities from malaria, HIV, and TB. In response to this critical threat, the region has adopted the AMR Global Action Plan and the African Union Framework for Antimicrobial Resistance Control 2... more

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Problem Management Plus (PM+)
recommended

World Health Organization WHO (2016) C_WHO

Individual psychological help for adults impaired by distress in communities exposed to adversity. The manual describes a scalable psychological intervention called Problem Management Plus (PM+) for adults impaired by distress in communities who are exposed to adversity. Aspects of Cognitive Behavi... more

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Enhancing mental health pre-service training with the mhGAP Intervention Guide: experiences and lessons learned

World Health Organization WHO (2020) C_WHO

This document was designed to inform educators, amongst others, about enhancing the pre-service curriculum with mental health Gap Action Programme Intervention Guide (mhGAP-IG) materials, which can provide future professionals with the theoretical and clinical knowledge they need to provide mental h... more

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Global Land Outlook Second Edition: Land Restoration for Recovery and Resilience

UN Convention to Combat Desertification (2022) CC

27 April 2022 Chronic land degradation: UN offers stark warnings and practical remedies in Global Land Outlook 2. GLO2 offers hundreds of examples from around the world that demonstrate the potential of land restoration. The way land resources – soil, water and biodiversity – are currently mi... more

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Guidelines for drinking-water quality: small water supplies - Executive summary

World Health Organization WHO (2024) C_WHO

The Guidelines for drinking-water quality: small water supplies have been developed to address the needs and opportunities associated with small supplies to facilitate progressive improvement towards safe and sustainable drinking-water services for all. These Guidelines are based on the principal re... more

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HIV/AIDS treatment and care in Belarus

J. D. Lundgren; D. Raben; I. Eramova; V. Ilyenkova World Health Organization (Europe); Centre for Heath & Infectious Disease Research (2014) C_WHO

Evaluation report January 2014

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Analysing the response of a Teacher Training Institution to HIV and AIDS: A case study from Zambia

Lucinda Ramos UNESCO (2007) CC

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WHO implementation tool for pre-exposure prophylaxis of HIV infection - Module 9

World Health Organization (WHO) World Health Organization (WHO) (2017) C_WHO

Module 9 Strategic planning July 2017 Module 9: Strategic planning. As WHO recommends offering PrEP to people at substantial HIV risk, this module offers public health guidance for policy-makers on how to prioritize services, in order to reach those who could benefit most from PrEP, and in wh... more

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Community Health Volunteers' Decision Support System Project

P. Bakibinga, Kamande E. , Kisia L., et al. African Population and Health Research Centre APHRC (2018) C1

This report presents the key findings of the end-of-project assessment of households and community health volunteers, conducted in 2017 in the Kamukunji and Embakasi sub-counties of Nairobi, Kenya, for a Community Health Volunteers’ Decision Support System (CHV DSS) intervention project. The re... more

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Toolkit on disability for AFRICA: FRAMEWORKS FOR IMPLEMENTING AND MONITORING THE UNITED NATIONS CONVENTION ON THE RIGHTS OF PERSONS WITH DISABILITIES

United Nations Division for Social Policy Development (DSPD) & United Nations Department of Economic and Social Affairs (DESA) (2016) C1

Module 2

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OCHA Policy Brief on Gendered Drivers, Risks and Impacts of Food Insecurity in the Sahel and the Horn of Africa

UN Office for the Coordination of Humanitarian Affairs (2023) CC

It is widely understood that the food insecurity crisis in the Sahel and the Horn of Africa is one of the world’s fastest growing and most neglected crises. It lacks sufficient global focus, resources and urgency. As in so many crises, women and girls are disproportionately affected and shoulder t...he consequences of protracted neglect, with unconscionable impacts on their safety, life chances and agency. Gaining a holistic view of the gendered drivers, risks and impacts of food insecurity in the Sahel and the Horn of Africa is difficult. This is due to a lack of data and prioritization, and the large geographical and socioeconomic terrain covered by both regions. However, what we do know about this crisis is more than enough to urgently address the needs of women and girls. An OCHA discussion paper on this topic (which will be published imminently, and from which this policy brief is drawn) found that there is: A strong risk of profound regression in gender equality gains made to date in the countries of concern, including on education, sexual and reproductive health, and the economic independence of women and girls (with knock-on effects on broader humanitarian and development outcomes). An increasing challenge to reverse what must be recognized as a protracted and growing gender-based violence (GBV) emergency in the Sahel and the Horn of Africa. The food insecurity crisis in the Sahel and the Horn of Africa is protracted, multidimensional and highly gendered, with spiralling impacts on gender equality and food security outcomes. It is driven by interwoven and overlapping factors, including climate change, political instability, conflict, socioeconomic conditions, migration and displacement and, more recently, COVID-19 and the war in Ukraine. Interlinked with these factors are gendered structural drivers of food insecurity, including deeply entrenched gender inequalities and harmful social norms. Gendered risks and impacts of food insecurity include alarming limitations on access to education, sexual and reproductive health rights, women’s agency and participation, and dramatic increases in different existing forms of GBV and the emergence of new ones. Recognition of such gendered dimensions of food insecurity and of the need for a multisectoral approach in the response is key to addressing the crisis, along-side sustained commitment and adequate allocation of resources. This policy brief draws out key findings from the OCHA discussion paper on this topic, which includes a desk review of studies, assessments and reports, and interviews with local women’s organizations on the front lines of the food insecurity crisis in communities across both regions. Below are the most pressing gendered drivers, risks and impacts of food insecurity (not in order of priority), as well as key gaps in the current humanitarian response to food insecurity, and recommendations to take forward. more

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Africa, WASH, and the Millennium Development Goals: A Local Systems Case Study of How Senegal Achieved MDG Target 7c

McGahey, Christopher USAID (2017) C1

Nationally, Senegal met the MDG target for water supply access. It did this by engaging the public and private sectors to effectively invest and report on investments. It focused on larger population centers, less on remote regions of the country. Its achievements set the stage for more equitable an... more

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National Community Health Worker Strategy in Zambia

Ministry of Health, Zambia (2010) C1

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Transmission dynamics and control of Ebola virus disease (EVD): a review

Chowell and Nishiura (2014)

BMC Medicine 2014, 12:196 http://www.biomedcentral.com/1741-7015/12/196

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Standard treatment guidelines acute sinusitis (India)

Ministry of Health & Family Welfare, India (2017) C1

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The West African Initiative for Climate-Smart Agriculture (WAICSA)

Chiriac, D.; et al. GIZ; Bloomberg Philatrhopies, IFAG; et al. (2019) CC

The Lab identifies, develops, and launches sustainable finance instruments that can drive billions to a low-carbon economy. The 2019 Global Lab Cycle targets four specific sectors across mitigation and adaptation: blue carbon in marine & coastal ecosystems; sustainable agriculture for smallholde... more

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“Female genital schistosomiasis is a sexually transmitted disease”: Gaps in healthcare workers’ knowledge about female genital schistosomiasis in Tanzania

Mazigo, H.; Samson, A.; Lambert, V. et al. PLoS Global Public Health (2022) CC

Female Genital Schistosomiasis (FGS) is a gynaecological disease caused by Schistosoma haematobium, a parasitic worm that is acquired by skin contact with freshwater contaminated by schistosome cerceriae. Communities in which the infection is most endemic have limited access to clean water and healt... more

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FACTI Panel Interim Report

The High-Level Panel on International Financial Accountability, Transparency and Integrity for Achieving the 2030 Agenda (FACTI Panel) The High-Level Panel on International Financial Accountability, Transparency and Integrity for Achieving the 2030 Agenda (FACTI Panel) (2020) CC

The High-Level Panel on International Financial Accountability, Transparency and Integrity for Achieving the 2030 Agenda (FACTI Panel) was convened by the 74th President of United Nations General Assembly and the 75th President of the Economic and Social Council on 2 March 2020. The objective of the... more

Problem Management Plus (PM+) recommended

Problem Management Plus (PM+)
recommended