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The resurgence of mpox in multiple African countries since 2022 has highlighted urgent gaps in preparedness, detection, and response capacities across the continent. While the mpox outbreak was initially classified as a Public Health Emergency of International Concern (PHEIC) and a Public Health Eme
...
rgency of Continental Security (PHECS), the risk of continued transmission in high-risk areas of Africa remains significant, particularly due to persistent zoonotic reservoirs, cross-border spread, and fragile surveillance systems.
more
The lack of an African research ethics framework during epidemic emergencies (EE) has been a glaring concern
amongst African scholars for decades. In the context of major public health emergencies of continental and global health concern over the last five years, such as Ebola in 2019, COVID in 202
...
0 and Mpox in 2024, and ongoing epidemics, including those of pandemic potential, the need for such a framework is evident. Ethics frameworks for research during emergencies have been published (World Health Organisation, 2016; Nuffield Council on Bioethics, 2020). However, there is currently no African and continent-wide, coherent guidance that promotes African values, elaborated by Africans for hosting research during EE on the continent. To address this gap, the African Centre for Disease Control convened an Ethics Working Group (Ethics WG) to develop an African
framework that embraces dominant African principles/values that might guide the ethical conduct of research in
more
Apenas 3% da investigação global em saúde provém de África, apesar da sua quota de 18% da
população mundial e de 25% da carga de doença. Um desafio para esta investigação limitada
em saúde no continente decorre do deficiente quadro de ética de investigação e da falha dos
princípios
...
internacionais de ética na investigação em proteger de forma óptima os participantes
africanos da investigação. As populações africanas possuem culturas, valores, sistemas de
crenças e virtudes peculiares que necessitam de ser explorados e compreendidos no processo
de conduta ética na investigação. Por exemplo, um estudo realizado num contexto africano
reportou que a informação sobre os diagnósticos de cancro como desfavorável durante o
processo de consentimento informado poderia alterar o tratamento e o resultado dos cuidados
aos doentes. Nos contextos africanos, ao contrário dos países desenvolvidos, a ênfase é
colocada na autonomia comunitária em detrimento da autonomia individual. Nas populações
africanas onde os níveis de literacia em saúde são comparativamente baixos, a compreensão da
investigação e da doença durante o consentimento informado pode comprometer a capacidade
de tomar decisões informadas. Além disso, o menor estatuto socioeconómico das populações
africanas pode tornar os participantes do estudo vulneráveis, dado que os incentivos oferecidos
podem afectar as suas decisões de participar no estudo.
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