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The ACT-Accelerator: Two years of impact

World Health Organization WHO (2022) C_WHO
The two-year impact report for the Access to COVID-19 Tools (ACT) Accelerator details impact, case studies and timelines of key milestones for the Diagnostics, Therapeutics and Vaccines pillars, as well as the Health Systems and Response Connector.
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Pharmaceutical pollution of the world’s rivers

Wilkinson, J.L.; A.B. A. Boxall, D. W. Kolpin, et al. (2022) CC
PNAS 119 (8) e2113947119 | https://doi.org/10.1073/pnas.2113947119 Environmental exposure to active pharmaceutical ingredients (APIs) can have negative effects on the health of ecosystems and humans. While numerous studies have monitored APIs in rivers, these employ different analytical methods, m... more
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Nurses and midwives: a vital resource for health

World Health Organization WHO, Regional Office of Europe (2022) C_WHO
This European compendium was produced to provide operational examples of the new nursing and midwifery roles and new service delivery models currently being employed across the Region. The case studies directly relate to the priority areas in Health 2020 and exemplify the types of activities needed ... more
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Water, Sanitation and Hygiene: The foundation for building resilience in climate‑vulnerable communities

Omasete J., Forster J., Geere J., et al. Water Aid (2022) CC
This report, which involved input from across WaterAid, in particular from the Programme Support Unit (PSU) of WaterAid UK, includes case studies from a variety of countries, including Bangladesh, Burkina Faso, Eswatini, Ethiopia, Ghana, India and Nepal, each demonstrating what must be done now to i... more
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Ongoing Living Update of COVID-19 Therapeutic Options: Summary of Evidence, Rapid Review 22 February 2022
recommended

Pan American Health Organisation PAHO (2022) C_WHO
This document includes the results of a rapid systematic review of current available literature. The information included in this review reflects the evidence as of the date posted in the document. In recognition of the fact that there are numerous ongoing clinical studies, PAHO will periodically up... more
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Advisory for Rational use of Remdesivir for COVID-19 Treatment

Ministry of Health& Family Welfare, Goverment of India (2021) CC
The purpose of this document is to stop to irrational use/ over prescription of this reserve/ experimental/ emergency use authorisation drug Remdesivir. For this reason, Joint Monitoring Group under Chairmanship of DGHS took into consideration findings of the followi... more
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Optimizing active case-finding for tuberculosis

World Health Organization. Regional Office for South-East Asia (2021) C_WHO
he WHO South-East Region in 2019 accounted for nearly a million missing TB patients from the estimated incidence. Active case-finding (ACF) or systematic screening for tuberculosis is an important tool to reach out to missing TB patients. When appropriately implemented, the activity is cost effectiv... more
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How to respond to vocal vaccine deniers in public: best practice guidance
recommended

World Health Organization WHO, Regional Office of Europe (2021) C_WHO
This guidance document provides basic principles for a spokesperson of any health authority on how to respond to vocal vaccine deniers. The suggestions are based on psychological research on persuasion, on research in public health, communication studies and on WHO risk communication guidelines.
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Online Course: Climate Change Negotiations and Health

World Health Organization (WHO), the United Nations Institute for Training and Research (UNITAR) and Climate Tracker (2021) C_WHO
This free online course on Climate Change Negotiations and Health features key information on climate change and its impacts on human health, provides an overview of the international climate change negotiations so far, and considers entry points to address health issues and priorities within climat... more
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Estimating COVID-19 vaccine effectiveness against severe acute respiratory infections (SARI) hospitalisations associated with laboratory-confirmed SARS-CoV-2

World Health Organization WHO (2021) C_WHO
Many critical questions remain about the effectiveness of COVID-19 vaccines in real-world settings. These questions can only be answered in post-introduction vaccine effectiveness studies.This guidance document outlines an approach to leverage existing surveillance systems for Severe Acute Respirato... more
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Strengthening mental health responses to COVID-19 in the Americas: A health policy analysis and recommendations

A. Tausch; Oliveira e Souza, R.; Martinez Viciana, C.; et al. Pan American Health Organization (2021) CC
The COVID-19 pandemic is having a major impact on the mental health of populations in the Americas. Studies show high rates of depression and anxiety, among other psychological symptoms, particularly among women, young people, those with pre-existing mental health conditions, health workers, and p... more
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Covid-19 - living NMA initiative

World Health Organization WHO, et al. (2021) C_WHO
As of January 20, 2021 the Covid-19 - living NMA initiative collected 150 RCTs and 36 non-randomised studies of vaccines from the ICTRP. 93 of these trials are recruiting patients.
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Interim guidance on selecting, commissioning and using freeze-preventative vaccine carriers

World Health Organization WHO (2021) C_WHO
Interim Guidance, published 11 January 2021. The cold chain is necessary to prevent damage to vaccines caused by heat exposure. However, improper use of cold chain equipment may cause damage to freeze-sensitive vaccines (i.e. those vaccines containing alum adjuvant or oil-emulsion adjuvant). Studie... more
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Data synthesis: public perceptions of the COVID-19 vaccinations

Niederberger,E.; V. Turmine, C. Homm RCCE Collective Service (2021) CC
A series of data syntheses from the RCCE Collective Service. It focuses on public perceptions of the COVID-19 vaccinations, bringing together 66 data sources from quantitative surveys across 107 countries and six regions, underpinned by a rapid review of additional studies and community feedback dat... more
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A situational analysis of programmatic management of TB preventive treatment in the WHO South-East Asia Region

World Health Organization WHO (2020) C_WHO
Tuberculosis (TB) prevention is essential for reaching the End TB targets in the South-East Asia Region (SEAR) of World Health Organization (WHO)1. The targets of 80% reduction in TB incidence rate and 90% reduction in TB mortality by 2030 (compared to 2015 levels) can be achieved only with addition... more
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The Boston Medical Center Patient Navigation Toolkit

The Boston Medical Center AVON Foundation for Women The Boston Medical Center AVON Foundation for Women (2020) C1
This toolkit is designed to help you plan and implement a Patient Navigation program with the best chance of reducing health disparities and improving health outcomes for your patients. It contains evidence-based and experience-based examples, case studies, practical tools, and resources to help you... more
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HIV drug resistance surveillance in countries scaling up pre-exposure prophylaxis

World Health Organization WHO (2020) C_WHO
WHO recommends that pre-exposure prophylaxis (PrEP) be offered as an additional prevention choice for HIV-negative individuals at substantial risk of HIV infection as part of combination prevention approaches. HIV drug resistance has been rarely reported among PrEP users who tested HIV positive i... more
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Recommendation regarding the use of Ivermectin as a treatment for COVID-19
recommended

Pan American Health Organization PAHO, World Health Organization WHO (2020) C_WHO
A recent study informed that ivermectin was successfully used in vitro for the treatment of SARS-CoV-2 in experimentally infected cells and two preprint publications on observational clinical studies reported the apparent utility of ivermectin to treat patients with COVID-19 needing mechanical venti... more
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Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis
recommended

Chu, D.K.; E.A Akl, S. Duda, et al. (2020) CC
a systematic review and meta-analysis Derek K Chu et al. on behalf of the COVID-19 Systematic Urgent Review Group Effort (SURGE) study authors. Published: The Lancet June 01, 2020 DOI: https://doi.org/10.1016S0140-6736(20)31142-9 'We did a systematic review of 172 observational studies in health-... more
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HIV Toolbox
recommended

MEDBOX (2020) CC
We have created a special Toolbox on HIV, please click here to see all guidelines, manuals, reports & studies