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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Key Messages for Safe School Operations In Countries with Outbreaks of Ebola

UNICEF; CDC; WHO (2015)

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Recovering from the Ebola Crisis

Magdy Martínez-Solimán; Abdoulaye Mar Dieye; Izumi Nakamitsu et al. United Nations, The World Bank, European Union and African Development Bank (2015)

Full Report. In response to a call by the United Nations Secretary-General and the Governments of Guinea, Liberia and Sierra Leone, an international team conducted an Ebola Recovery Assessment. The aim was to contribute towards laying the foundation for short-, medium- and long-term recovery while ... more

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WHO manual for HIV drug resistance testing using dried blood spot specimens

World Health Organization WHO (2020) C_WHO

HIV-1 drug resistance (HIVDR) genotyping is an essential component of the WHO global HIVDR surveillance strategy. Plasma “gold standard” specimen type for HIVDR genotyping, but its use may not be feasible in rural, remote areas in low- and middle-income countries, since preparing and storing it ... more

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WHO country cooperation strategy 2014-2018, Myanmar

World Health Organization (WHO), Country Office for Myanmar (2014) C_WHO

The strategic priorities of the CCS 2014–2018 are:
(1) Strengthening the health system.
(2) Enhancing the achievement of communicable disease control targets.
(3) Controlling the growth of the noncommunicable disease burden.
(4) Promoting health throughout the life course.
... more

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The compound impact of extreme weather events and COVID-19

Walton D., Arrighi J., et al. IFRC - International Federation of Red Cross (2021) C2

From the start of the COVID-19 pandemic until August 2021, extreme weather events have affected at least 139.2 million people and killed at least 17,242 people in at least 433 unique events. These figures are certainly an underestimate, as they do not include estimates of numbers of people affected ... more

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National Guidelines for the Use of Antiretroviral Therapy in Adults and Adolescents

National Center for HIVAIDS, Dermatology and STD, Cambodia Ministry of Health (2012) CC

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COVID-19 and Food Safety: Guidance for Food Businesses

World Health Organization WHO (2020) C_WHO

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Philippines: A Training Manual for Health Workers on Healthy Lifestyle - Promoting Mental Health (Module 6/6)

WHO and DOH Philippines (2009) C_WHO

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Community Health Extension Workers Strategy in Uganda (2015/16- 2019/20)

Ministry of Health, Republic of Uganda (2016) C1

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Behavorial Health Departement - Primary Care Center and fireweed Treatment Guidelines for PTSD

Sorkin, J., Chaney, G., Garcia, M.,et al. (2006) C2

This treatment guideline is intended to assist clinicians in the Behavioral Health department in treatment planning and service delivery for patients with Post Traumatic Stress Disorder (PTSD). It may also assist clinicians treating patients who have some of the signs and symptoms of PTSD but who do... more

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Diagnostics, therapeutics, vaccine readiness, and other health products for COVID-19
recommended

World Health Organization WHO (2021) C_WHO

Interim Guidance, 12 July 2021; This tool was developed to assess present and surge capacities for the treatment of COVID-19 in health facilities. It allows health facilities to assess the availability and status of stockout of critical COVID-19 medicines, equipment and supplies on site and to ident... more

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Information and Communications Technology Response to the Liberia Ebola Crisis

USAID; Net Hope; GBI (2014)

Desk Review and Recommendations for Private Sector Engagement

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HIV/AIDS treatment and care in Belarus

J. D. Lundgren; D. Raben; I. Eramova; V. Ilyenkova World Health Organization (Europe); Centre for Heath & Infectious Disease Research (2014) C_WHO

Evaluation report January 2014

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Community Health Workers in Sub Saharan Africa
recommended

Hannah Faal, Rènée du Toit, Henrietta Monye, Ronnie Graham IAPB Africa (2016) CC

A booklet on how CHWs were addressing eye health across Africa based on desk research and a survey in 23 countries

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Module: Other significant mental health complaints

WHO WHO (2015) C_WHO

Overview Learning objectives • Promote respect and dignity for people with other significant mental health complaints. • Know the common presentation of other significant mental health complaints. • Know the assessment principles of other significant mental health complaints. • Know the... more

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A glimpse into WHO work in Botswana

World Health Organisation (WHO) (2023) C_WHO

This publication articulates the WHO Botswana Country Office’s focus and investment needs for the biennium 2022–2023, building on achievements, networks, and partnerships fostered in 2020-2021. As the leading health authority within the United Nations system in Botswana, the WHO Country Offi... more

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DRR Working Group Strategic Framework 2013–2018

DRR [Disaster Risk Reduction] Working Group Myanmar (2014) C1

The changes occurring in Myanmar highlight the need to have a robust DRR network that can support the Government as well as the communities in their efforts to build a resilient Myanmar. To this end, the DRR WG devised and facilitated a multi-stakeholder process aiming to develop its Strategic Frame... more

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Health interventions for older people in emergencies

Fritsch, P. Help Age International; ECHO (2013) CC

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Policy Brief: The impact of COVID-19 on older persons

United Nations (2020) C2

The COVID-19 pandemic is causing untold fear and suffering for older people across the world. As of 26 April, the virus itself has already taken the lives of some 193,710 people, and fatality rates for those over 80 years of age is five times the global average. As the virus spreads rapidly to devel... more

Diagnostics, therapeutics, vaccine readiness, and other health products for COVID-19 recommended

Community Health Workers in Sub Saharan Africa recommended

Diagnostics, therapeutics, vaccine readiness, and other health products for COVID-19
recommended

Community Health Workers in Sub Saharan Africa
recommended