Pathogens . 2021 Nov 16;10(11):1493.doi: 10.3390/pathogens10111493
.Chronic manifestations of Chagas disease present as disabling and life-threatening condi-tions affecting mainly the cardiovascular and gastrointestinal systems. Although meaningful research has outlined the different molecular mech...anisms underlying Trypanosoma cruzi’s infection and the host-parasite interactions that follow, prompt diagnosis and treatment remain a challenge, particu-larly in developing countries and also in those where the disease is considered non-endemic. This review intends to present an up-to-date review of the parasite’s life cycle, genetic diversity, virulence factors, and infective mechanisms, as well as the epidemiology, clinical presentation, diagnosis, and treatment options of the main chronic complications of Chagas disease.
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The publication of the of the Antimicrobial Treatment Guidelines represents the
culmination of the efforts of the Antimicrobial Stewardship Program of ICMR to publish treatment guidelines for common syndromes in India. These guidelines are targeted for the health care settings. It aims to rationali...ze the usage of antibiotics on our Essential Medicines Formulary (EMF) and to establish consistency in the treatment of various infectious conditions.
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Objective: To conduct a landscape assessment of public knowledge of cardiovascular disease risk factors and acute myocardial infarction symptoms, cardiopulmonary resuscitation (CPR) and automated external defibrillator (AED) awareness and training in three underserved communities in Brazil.
Metho...ds: A cross-sectional, population-based survey of non-institutionalised adults age 30 or greater was conducted in three municipalities in Eastern Brazil. Data were analysed as survey-weighted percentages of the sampled populations.
Results: 3035 surveys were completed. Overall, one-third of respondents was unable to identify at least one cardiovascular disease risk factor and 25% unable to identify at least one myocardial infarction symptom. A minority of respondents had received training in CPR or were able to identify an AED. Low levels of education and low socioeconomic status were consistent predictors of lower knowledge levels of cardiovascular disease risk factors, acute coronary syndrome symptoms and CPR and AED use.
Conclusions: In three municipalities in Eastern Brazil, overall public knowledge of cardiovascular disease risk factors and symptoms, as well as knowledge of appropriate CPR and AED use was low. Our findings indicate the need for interventions to improve public knowledge and response to acute cardiovascular events in Brazil as a first step towards improving health outcomes in this population. Significant heterogeneity in knowledge seen across sites and socioeconomic strata indicates a need to appropriately target such interventions.
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The COVID-19 pandemic has impacted regular cardiovascular healthcare access and delivery. Service utilisation has declined, and excess cardiovascular mortality has been reported in several countries. We aim to estimate excess cardiovascular deaths in Chile during 2020.
This report contains the results of an in-depth Training Needs Assessment (TNA) of Health Workers in the 4 project counties of the republic of Kenya – Nakuru, Kisumu, Nairobi and Bungoma. The assessment, facilitated by the UPOPs Project in close collaboration with the Ministry of Health and Minist...ry of Environment and Natural Resources, took place in the month of September 2017. This assessment focused on health workers at County and County referral health facilities.
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The conduct of COVID-19 vaccine trials in the context of a candidate vaccine being issued with Emergency Use Designation raises challenging ethical questions, including in relation to the use of placebo controls and unblinding of trial participants in current and future COVID-19 vaccine trials. This... policy brief was developed by the WHO Access to COVID-19 Tools (ACT) Accelerator Ethics & Governance Working Group, to provide guidance for researchers, sponsors, regulators, research ethics committees, and policy-makers, on these and related issues.
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This toolkit has been developed by the ZAZI campaign for use by peer educators, community outreach workers, faith-based organisations, and traditional health practitioners to help facilitate participatory discussions on sexual and reproductive health with women aged between 20 and 49 years of age. T...he toolkit is divided in 10 content sections
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Long-lasting insecticidal nets (LLINs) treated with a pyrethroid insecticide and the synergist piperonyl butoxide (PBO) have become available. Two of these nets (Olyset®Plus and PermaNet®3.0) have a WHO Pesticide Evaluation Scheme (WHOPES) interim recommendation as LLINs
Prequalification of Male Circumcision Devices
PQMC_007 v1 16 December 2011
La présente analyse du projet HPP a pour objectifs spécifiques de documenter (1) les sources d’approvisionnement existantes des contraceptifs ; (2) l’implication des agents par catégorie dans la proposition de médicaments et de contraceptifs ; (3) les politiques et les directives actuelles d...u gouvernement concernant la distribution des contraceptifs et (4) les suggestions des participants pour améliorer le partage des tâches des services de planification familiale à base communautaire et les produits de PF.
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Цель: оценить этиологическую структуру симптоматической эпилепсии, возрастную структуру периода манифестации заболевания, среднюю длительность латентного пери...да среди детей с различным характером повреждений, зависимость частоты приступов от характера повреждения. Материал и методы. Изучались 180 медицинских карт пациентов, имевших симптоматическую и криптогенную формы заболевания. Анализ заключался в оценке анамнестических данных, параметров ЭЭГ-исследований и нейровизуализации. Результаты. Установлено преобладание гипоксически-ишемической энцефалопатии в этиологической структуре заболевания. Возраст манифестации чаще приходился на период от года до 3 лет. Наиболее частой локализаци-
ей эпилептогенного очага явилась область височной и лобной доли. Наиболее длительный латентный период отмечен при ЧМТ, а наиболее короткий — при нейроинфекциях и последствиях внутриутробных инфекций. Заключение. Симптоматическая эпилепсия у детей является многофакторным заболеванием, течение и проявление которого в значительной мере зависят от инициального повреждения, вызвавшего данную патологию.
http://www.ssmj.ru/system/files/2014_02_318-319.pdf
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Vision 2030
Accessed: 17.11.2019
The Government of Kenya, through the Ministry of Health, has the
constitutional obligation to provide the highest level of health care for its
citizens. The Ministry of Health’s review of the 2015 Policy document
on infection prevention and control (IPC) is in line with that goal.
Healthcare Waste Management Toolkit for Global Fund Practitioners and Policy Makers. Part B
These guidelines have been compiled for education ministries or other educational leaders (including development partners, non-governmental or private organizations working with schools or directly with caregivers) who want to adapt and adopt resources to support the marginalized caregivers of child...ren with disabilities.
The guidance presented in this document was developed by a team of international and national experts following a proof-of-concept pilot4 of the resources in two countries. The work was carried out between February 2021 and January 2022. The pilots demonstrated that principles and activities described in the resources could be carried out, in practical terms, in line with existing government programmes supporting the implementation of disability-inclusive education.
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