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1
Front. Public Health, 16 May 2023 Sec. Infectious Diseases: Epidemiology and Prevention Vol.11
PLoS ONE 18(12): e0295920. https://doi.org/10.1371/journal.pone.0295920. PLHIV were largely unaware and sceptical of U = U as the message appeared to contradict
the mainstream HIV prevention clinical guidance.
WHO's Department for HIV, Tuberculosis, Hepatitis and Sexually Transmitted Infections (STIs) has consolidated all existing normative guidance on STIs into a single publication. Structured around 10 chapters that follow the STI prevention and care ca
...
scade, the handbook covers primary prevention, syndromic management and asymptomatic case identification, diagnostics, treatment, partner management, surveillance, service delivery, and integration within primary health care, community-based clinics, or other platforms (HIV, sexual health, antenatal clinics, etc).
more
This implementation brief addresses integration of HIV testing services into family planning (FP) services. It is intended as a practical resource for national health programmes seeking to introduce or scale up HIV testing and linkage to HIV prevention
...
, sexually transmitted infection, and antiretroviral therapy services in FP.
This document highlights emerging good practices and country experiences of integrated HIV prevention and testing services within FP and advocates for increased linkage for FP clients to HIV services according to their needs. It also brings together information on models of integration of HIV testing into FP services, programme examples from east and southern Africa and guidance on the implementation monitoring process.
more
The updated guidelines present a standard minimum dataset, priority indicators and recommendations to strengthen data use across HIV prevention, testing and treatment, and linkages to services for sexually transmitted infections, viral hepatitis, tu
...
berculosis and cervical cancer. The guidelines also cover the use of routinely collected data for HIV surveillance (including measurement of HIV prevalence and incidence) and emphasize the use of data from different sources to gain a better picture of epidemiologic trends. The whole collection you can download from here https://www.who.int/publications/i/item/9789240055315
more
Mathematical modelling of lenacapavir: landscaping review on impact and cost–effectiveness
recommended
Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis. Web Annex E
Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis. Web Annex G Abstract
HIV drug resistance strategies focus on prevention through adherence and treatment optimization, surveillance to monitor resistance trends, and innovation in new drugs and diagnostics. Key approaches include implementing national action plans, stren
...
gthening laboratory capacity for monitoring, and providing comprehensive care, especially for vulnerable populations
more
Adolescent girls and young women (AGYW) remain disproportionately affected by HIV in Eastern and Southern Africa (ESA), with 26 per cent of new infections attributed to this population. AGYW face many personal, social and structural barriers to access, uptake and use of traditional HIV
...
prevention methods. Oral Pre-exposure Prophylaxis (PrEP) is proven to be highly effective as an additional prevention choice for reducing the risk of HIV acquisition, including for AGYW. Successful uptake and adherence to PrEP is critical in its effectiveness as an HIV prevention method, however, the current demand for PrEP by AGYW is low with suboptimal adherence.
Within the ESA region, there is currently great impetus to address these challenges and scale up PrEP for AGYW. A critical aspect of this is to leverage the learnings and evidence from implementation of how to improve the demand and quality of PrEP programming for this population. Improving the Quality of Pre-Exposure Prophylaxis Implementation for Adolescent Girls and Young Women in Eastern and Southern Africa examines the current efforts in the region to accelerate and scale up evidence-based PrEP delivery platforms. The implementation brief provides current knowledge and builds on WHO guidance to provide key considerations for implementation, including driving demand and improving quality, as well as focus on wider combination prevention and integration agendas.
more
Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis. Web Annex F
PLoS One 20(5): e0319807. https://doi.org/10.1371/journal.pone.031980
The implementation of people-centered, evidence-driven, culturally, and religiously
sensitive program enabled SFH to reach a high number of AP in northern Nigeria. This
helps improve equity in access to care by AP. There are sp
...
ecific program areas that need
continuous improvement including strategies to reach MSM to avoid the evolution of
new structural barriers; expansion of PWID programming to optimize all aspects of harm
reduction; and sustained sensitization, education, and awareness creation among AP to
improve uptake of PrEP and other prevention and care services.
more
WHO recommends that pre-exposure prophylaxis (PrEP) be offered as an additional prevention choice for HIV-negative individuals at substantial risk of HIV infection as part of combination prevention
...
approaches.
HIV drug resistance has been rarely reported among PrEP users who tested HIV positive in randomized controlled trials or open-label studies. However, PrEP-selected HIV drug resistance could potentially negatively impact the effectiveness of treatment options among PrEP users who acquire HIV, since there is a potential for overlapping resistance profiles between antiretroviral drugs used for both PrEP and first-line antiretroviral therapy.
more
Understand HIV transmission, prevention strategies, and treatment advances including antiretroviral therapy and PrEP. Access medical lectures and research updates on YouTube from Harvard, medical professionals, and health organizations covering drug
...
resistance, vaccine development, and co-infections.
more
Modelling shows that it will be essential to complement lenacapavir with additional prevention options, testing and treatment. See “Meeting reports” at https://www.unaids.org/en/resources/publications/all for a description of models and tools to
...
estimate potential impact and quantifications required for lenacapavir
more
This brief report summarizes recent information on HIV drug resistance (HIVDR) in the era of integrase-strand transfer inhibitors (INSTI) for HIV prevention and treatment.
Impact of PEPFAR Stop Work Orders on PrEP
recommended
The widespread termination of US government contracts and PEPFAR stop work orders have had a devastating impact on access to HIV prevention. To find out more about what happened and understand the ongoing impacts in detail, click on the link
Questions and answers. A key priority is preventing the interruption of current HIV treatment and prevention medicines. This Q&A outlines advice when this is not possible. Available in Arabic, Chinese, English, French, Portuguese, Russian and Spanis
...
h
more
Helping Children Live with HIV offers a holistic approach by building on the existing knowledge of parents and caregivers and respecting the importance of other local resources. It integrates health care, illness prevention, and psychosocial support
...
for children and families coping with poverty, food insecurity, emotional trauma, loss, as well as stigma and discrimination.
This guide is intended for broad use by parents, family members, and health workers in home settings and throughout community-based health programs.
To learn more, view the table of contents and a sample chapter, and to buy your copy of this essential new resource from Hesperian.
more
Adolescents and young adults aged 10-24 remain underserved in the global response against HIV. Combination prevention, treatment and care programmes use a mix of evidence-based interventions to meet the current HIV
...
prevention needs of adolescents and young adults. However, there needs to be a focus on priority interventions that are evidence-based, practical, contextual and sustainable. This document highlights interventions and recommendations that have passed through the evidence-based lens of the WHO.
more
This brief from Audere and AVAC explains how artificial intelligence (AI) can support the HIV field by expanding reach, enhancing prevention, and improving care.
