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Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse. A systematic evidenc...e map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

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Antimicrobial stewardship programmes in health-care facilities in low- and middle-income countries. A WHO practical toolkit

World Health Organization WHO (2019) C_WHO

Stewardship is defined as “the careful and responsible management of something entrusted to one’s care”. It was originally applied in the health-care setting as a tool for optimizing antimicrobial use, termed “antimicrobial stewardship” (AMS). Stewardship has since be... more

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Averting risks to the food chain

FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS FAO (2019) C2

As the number of transboundary pest and animal and foodborne disease outbreaks rises, so does the number of people who are chronically hungry due to these and other factors. The correlation can be explained by the link between our health and that of the planet. We rely on land and sea for the produc... more

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Executive Summary - Conclusions and policy implications

United Nations Office on Drugs and Crime; World Drug Report 2017 (2019) C2

World Drug Report 2017 -1- Accessed: 14.03.2019

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Healthy environments for healthier populations: why do they matter and what can we do?

World Health Organisation WHO (2019) C_WHO

Known avoidable environmental risks to health cause at least 12.6 million deaths every year, and account for about one quarter of the global burden of disease (2016 data) (1). Air pollution alone causes about 7 million deaths a year, placing it among the top global risks to health (2). Global envir... more

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Antimicrobial movement from agricultural areas to the environment: The missing link

Jackson, J., Kheng Heng, L., Eklund, G. et al. Food and Agriculture Organization (FAO) (2019) C2

A role for nuclear techniques Antimicrobials play a critical role in the treatment of human and animal (aquatic and terrestrial) diseases, which has led to their widespread application and use. Antimicrobial resistance (AMR) is the ability of microorganisms to stop an antibiotic, such as an antimic... more

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Rational Use of Medicines: a review

Dutta, S. (2019) CC

World Journal of Pharmaceutical and Medical Research vol. 5 (2019) 3, 129-132

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Commercial foods for infants and young children in the WHO European Region

World Health OrganizationEurope (2019) C_WHO

In order to help Member States understand what commercial foods for infants and young children are currently on the market, and to support implementation of the Guidance on ending inappropriate promotion of foods for infants and young children at the European level, the WHO Regional Office for Europ... more

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Prevention and control of noncommunicable diseases in Kazakhstan. The case for investment

World Health Organization WHO (2019) C_WHO

Noncommunicable diseases (NCDs) such as cancer, cardiovascular disease, diabetes and chronic respiratory diseases and their risk factors are an increasing public health and development challenge in Kazakhstan. This report provides evidence through three analyses that NCDs reduce economic output and ... more

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National Voluntary Medical Male Circumcision Strategy 2014/15-1018/19

Ministry of Health, Kenya (2018) CC

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Good practice guide: embedding inclusion of older people and people with disabilities in humanitarian policy and practice

Supriya Akerkar and Rhea Bhardwaj ADCAP Age an& Disability Capactiy (2018) C1

Lessons learnt from the ADCAP programme | This guide shares good practices and challenges that have emerged through the experience of the Age and Disability Capacity Programme (ADCAP) implementing partners, in embedding inclusion of older people and people with disabilities within their humanitaria... more

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Compendium of WHO guidelines and associated standards: ensuring optimum delivery of the cascade of care for patients with tuberculosis
recommended

World Health Organization WHO (2018) C_WHO

2nd edition. T The Compendium has been developed as a clear and concise instrument to facilitate the understanding and planning of delivery of high-quality care for everybody affected by TB. It incorporates all recent policy guidance from WHO; follows the care pathway of persons with signs or sympt... more

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Classification of digital health interventions v1.0. A shared language to describe the uses of digital technology for health

World Health Organization (2018) C_WHO

The classification of digital health interventions (DHIs) categorizes the different ways in which digital and mobile technologies are being used to support health system needs. Historically, the diverse communities working in digital health—including government stakeholders, technologists, clinic... more

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WHO Namibia Biennial Report 2016-2017

World Health Organization WHO, Regional Office for Africa (2018) C_WHO

The 2016-2017 Biennial report presents an overview of WHO Namibia's main achievements and challenges and highlights its vision for the next five years.

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Menstrual Hygiene Management
recommended

Save the Children (2018) C2

Operational Guidelines. Guidelines for the development of educational programmes for MHM, including tips on the topics to address and methods to assess girls’ practices in a respectful way with practical tools

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HIV Prevention 2020 Road Map

UNAIDS (2018) C_WHO

Accelerating HIV prevention to reduce new infections by 75%

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56o Conselho director - 70a sessão do comitê regional da OMS para as Américas

Organização Pan-Americana da Saúde; Organização Mundial da Saúde (Américas) (2018) C_WHO

Tema 8.22 da agenda provisória Washington, D.C., EUA, 23 a 27 de setembro de 2018 CD56/INF/22 31 de agosto de 2018 Original: inglês/espanhol

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Translating Community Research Into Global Policy Reform For National Action

S. Dilmitis; A. Welbourn; F. Anam; et al. ICW Latina; ICW WA; UNAIDS; et al. (2018) C2

Translating Community Research Into Global Policy Reform For National Action: A Checklist For Community Engagement To Implement The WHO Consolidated Guideline On The Sexual And Reproductive Health And Rights Of Women Living With HIV 3rd edition | December 2018

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Social protection: a Fast-Track commitment to end AIDS

UNAIDS (Joint United Nations Programme on HIVAIDS); Unicef; World Health Organization; et al. (2018) C2

UNAIDS 2018 / Guidance Guidance for policy-makers, and people living with, at risk of or affected by HIV

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Towards intensified African Union–United Nations cooperation for the elimination of sexual and gender-based violence and protecting the health and rights of women and children in humanitarian settings

UNAIDS (Joint United Nations Programme on HIVAIDS); African Union; H6 Partnership (2018) C2

Vanquishing violence and vulnerability in humanitarian settings Background paper for the joint African Union–UNAIDS (in capacity of serving Chair of H6) high-level side event at the 73rd United Nations General Assembly, 24 September 2018, at UNHQ, Conference Room 3

Compendium of WHO guidelines and associated standards: ensuring optimum delivery of the cascade of care for patients with tuberculosis recommended

Menstrual Hygiene Management recommended

Compendium of WHO guidelines and associated standards: ensuring optimum delivery of the cascade of care for patients with tuberculosis
recommended

Menstrual Hygiene Management
recommended