Malaria in pregnancy is a significant health problem in malaria-endemic areas. It not only causes substantial childhood morbidity and mortality but also increases the risks of adverse events for pregnant women and their developing fetuses. Most of the burden in these areas is due to infection with P...lasmodium falciparum. Artemisinin-based combination therapy (ACT) has been recommended as first-line treatment for uncomplicated P. falciparum malaria in all populations, including pregnant women in their second and third trimesters, since 2006. However, for women in their first trimester of pregnancy, WHO recommended as first-line treatment a combination of quinine and clindamycin.
Based on a review of the evidence conducted in 2022, WHO now recommends artemether–lumefantrine, the ACT with the most human safety data available, as the preferred treatment for uncomplicated P. falciparum malaria in the first trimester of pregnancy. This document presents all relevant evidence on the effects and safety in early pregnancy of artemisinins and partner medicines used in ACTs from both studies in experimental animals and observational studies in humans.
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Front. Malar. 3:1336324. doi: 10.3389/fmala.2025.1336324
El propósito de esta guía es brindar orientaciones clínicas actualizadas en TB/VIH con énfasis en aspectos de diagnóstico, incluidas nuevas técnicas, así como de tratamiento vigente, sin perder de vista un enfoque de salud pública. Al recopilar y consolidar en una sola guía las últimas rec...omendaciones de la Organización Mundial de la Salud en el tema, se busca elaborar un documento de referencia y consulta frecuente, que unifique y estandarice el manejo de la coinfección TB/VIH de manera integral en establecimientos de salud con base en el principio de “dos enfermedades, un solo paciente”. También busca sustentar la actualización de normas y guías nacionales sobre la coinfeccion y complementar el trabajo coordinado que debe existir entre los programas de prevencion y control de TB y VIH a todo nivel en el marco las doce actividades de colaboración TB/VIH recomendadas internacionalmente.
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The purpose of this guide is to provide updated clinical guidance on TB/HIV, with an emphasis on diagnostic aspects—including new techniques—as well as current treatment, while maintaining a public health approach. By compiling and consolidating the latest World Health Organization recommendatio...ns on the subject into a single guide, the aim is to create a reference and consultation document that is frequently used, and that unifies and standardizes the comprehensive management of TB/HIV co-infection in healthcare facilities based on the principle of “two diseases, one patient.” It also seeks to support the updating of national standards and guidelines on co-infection and to complement the coordinated work that must exist between TB and HIV prevention and control programs at all levels, within the framework of the twelve internationally recommended TB/HIV collaborative activities.
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The article introduces Pf-HaploAtlas, a new online tool developed by MalariaGEN to track genetic mutations in the Plasmodium falciparum parasite—the most deadly malaria-causing species. This app allows researchers and public health professionals to explore global data on drug resistance mutations ...and genetic variation across thousands of parasite genomes. The tool is designed to improve understanding of how malaria parasites evolve and spread, and to support efforts in monitoring antimalarial drug resistance. With an intuitive interface, Pf-HaploAtlas enables users to visualize haplotype patterns, compare regional differences, and access up-to-date data that can inform control strategies and research.
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The WHO Malaria Threats Map is an interactive online platform that showcases the latest global data on four critical biological threats to effective malaria control and elimination: mosquito insecticide resistance, Plasmodium falciparum hrp2/3 gene deletions, antimalarial drug resistance, and the ...spread of invasive vector species. Designed for public health professionals and researchers, the map allows users to explore and filter data regionally, track emerging resistance patterns, and view visual trends. Its purpose is to inform strategies for surveillance, guide policy-making, and support efforts to eliminate malaria, particularly by anticipating and responding to biological challenges that could undermine control programs.
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Le document intitulé « Guide du conseiller – Renforcement des capacités de lutte contre le paludisme » est un guide pratique destiné aux conseillers techniques travaillant au sein des Programmes nationaux de lutte contre le paludisme (PNLP), principalement dans des pays partenaires souten...us par l’USAID. Il a pour objectif de fournir des orientations concrètes sur la manière d’appuyer efficacement les PNLP dans la gestion, la planification stratégique, la mise en œuvre des subventions du Fonds mondial et le renforcement des capacités organisationnelles et humaines. Le guide décrit le rôle des conseillers, les étapes de leur intégration, les outils d’évaluation de performance, ainsi que les bonnes pratiques pour collaborer avec les partenaires locaux. Il met l’accent sur une approche participative, le transfert de compétences et la durabilité des interventions, dans une perspective d’amélioration continue des systèmes de santé.
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Dans certaines parties d’Afrique, la transmission du paludisme a lieu principalement pendant les trois ou quatre mois de la saison des pluies. Environ 39 millions d’enfants de moins de cinq ans vivent dans les zones de transmission saisonnière, où on dénombre environ 34 millions de cas et où... plus de 150.000 enfants meurent chaque année. La CPS est une intervention préventive ciblant spécifiquement les enfants vivant dans ces régions. La CPS, appelée autrefois traitement préventif intermittent chez l’enfant, est « l’administration intermittente d’un traitement complet par un médicament antipaludique pendant la saison du paludisme afin de prévenir la
maladie, avec pour objectif de maintenir les concentrations sanguines du médicament antipaludique à des taux thérapeutiques pendant toute la période où le risque de paludisme est le plus élevé. »
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The presentation titled "Malaria Capacity Building Initiative" outlines efforts led by the WHO and partner organizations to strengthen the skills and systems needed to fight malaria globally. It highlights the need for a coordinated, long-term strategy to build human resource capacity in malaria-end...emic countries—especially among national malaria control programs, frontline health workers, NGOs, and WHO staff. The document reviews past and current training activities, such as workshops on case management, entomology, vector control, epidemiology, and planning. It emphasizes the development of standardized training materials and competency frameworks, the role of national and regional training centers, and the use of blended learning methods (e.g., e-learning and in-person sessions). The goal is not just to deliver training, but to build sustainable capacity through partnerships, continuous improvement, quality assurance, and integration into health systems. It also calls for better coordination, tracking of trained personnel, and engagement of ministries of finance to ensure long-term support.
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One of the world’s leading non-profit organisations specialising in the prevention, control and treatment of malaria and other communicable diseases among vulnerable populations. The Malaria Consortium website provides comprehensive information about the organization’s work in preventing, contro...lling, and eventually eliminating malaria and other communicable diseases. It showcases the organization’s projects, research, publications, and policy work across Africa and Asia. The site highlights areas such as disease surveillance, health system strengthening, seasonal malaria chemoprevention, and integrated community case management. It also serves as a platform to share news, technical resources, impact reports, and opportunities for collaboration. The target audience includes public health professionals, donors, researchers, and policy-makers interested in global health and infectious disease control.
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You can download the modules from the website
La surveillance, suivi et'évaluation (SSE) jouent un rôle vital dans tous les programmes de contrôle et de prévention du paludisme. Ce cours en ligne, offert par MEASURE Evaluation, fournit une introduction complète aux SSE des programmes de lutte contre le paludisme.
Téléchargez un PDF du c...ours complet ou téléchargez les modules individuels ci-dessous. Pour accéder au cours en ligne de certification
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The ECDC's Cholera Monthly Surveillance page provides up-to-date data on cholera cases reported in Europe and globally. It monitors outbreaks, tracks trends, and analyzes the spread of the disease to support public health responses. The page includes interactive maps, statistics, and reports to help... policymakers, researchers, and healthcare professionals understand cholera’s epidemiology and implement preventive measures.
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This is an update (third edition) of the BACPR Standards & Core Components and represents current evidence-based best practice and a pragmatic overview of the structure and function of Cardiovascular Prevention and Rehabilitation Programmes (CPRPs) in the UK. The previously described seven standards... have now been reduced to six but without sacrificing any of the key elements and with a greater emphasis placed on measurable clinical outcomes, audit and certification. Similarly, the second edition provided an overview of seven core components felt to be essential for the delivery of quality prevention and rehabilitation, and this too has been reduced to six. The interplay between cardio-protective therapies and medical risk factors is almost impossible to disentangle for the vast majority of patients and even if specific drug therapies are deployed exclusively for risk factor modulation, the indirect effect will also be cardio-protective. Thus, these have been combined into a single core component – medical risk management.
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Le Groupe spécial mondial de lutte contre le choléra (GTFCC) a lancé Mettre fin au choléra : Une feuille de route mondiale pour 2030 (la Feuille de route mondiale. Cette stratégie vise à réduire de 90 % le nombre de décès dus au choléra dans le monde et à mettre fin à la maladie dans a...u moins 20 pays d’ici 2030. Elle est organisée selon trois axes principaux :
• assurer une détection et une réponse précoces pour contenir les épidémies
• adopter une approche multisectorielle pour prévenir et contrôler le choléra dans les
points chauds
• mettre en place un mécanisme de coordination efficace de l’appui technique, la
mobilisation des ressources et des partenariats aux niveaux local et mondial.
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Le rapport décrit la situation épidémiologique au Congo entre le 22 et le 23 juillet 2023, mettant en évidence les épidémies de choléra, de shigellose et de salmonellose. Il mentionne 19 cas confirmés de choléra, 3 de shigellose et 3 de salmonellose, ainsi que 63 cas d'intoxication alimenta...ire. Au total, 36 décès ont été signalés, avec une majorité des cas concentrés à Dolisie. Les autorités sanitaires ont mis en place des mesures de riposte, notamment la distribution de matériel médical, la sensibilisation communautaire et la surveillance épidémiologique. Des défis persistent, notamment l’identification de la source de contamination et le renforcement des capacités médicales.
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For several years, agencies supporting preparedness and response to cholera outbreaks have supplied medicines and medical devices through the Interagency Diarrhoeal Disease Kits (IDDK).
In an effort to better align the presentation and content of the kits to field needs, the composition of the ch...olera kits has been reviewed by WHO and its partners in 2015 and again in 2020. The content of all modules have been slightly revised with no changes except for the cholera laboratory check list.
The revised cholera kits 2020 are designed to help prepare for a potential cholera outbreak and to support the first month of the initial response for 100 cases. The overall package consists of six different kits, each divided in several modules.
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A training manual for identifying, assessing, preventing and controlling the risks of pandemics in the workplace. This training manual has been developed for both medical and non-medical personnel who may be called upon to lead emergency response, (eg epidemic outbreak, etc), ensure effective conta...inment whiles work continues and essential goods and services continue to be supplied.
The manual provides insight into some of the local epidemics experienced in Ghana such as Cholera, Cerebrospinal meningitis (CSM) and Influenza(s), the causes, signs and symptoms and preventive measures with a view to increasing knowledge among management, staff and their families as well as immediate communities within which they work.
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Response to the Periodic EpidemicThe document "Zanzibar's Victory Against Cholera Epidemic" details the successful efforts taken by Zanzibar to control and eliminate cholera outbreaks. It highlights the strategies implemented, including improved water and sanitation infrastructure, public health cam...paigns, vaccination programs, and rapid response measures. The report emphasizes community engagement, government commitment, and international partnerships as key factors in combating the disease. Zanzibar's experience serves as a model for other regions facing similar public health challenges, demonstrating that sustained efforts in hygiene, disease surveillance, and emergency preparedness can effectively control cholera epidemics.
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The document is a comprehensive practical guide for managing cholera epidemics. It includes detailed instructions on outbreak investigation, control measures, case management, and the organization of treatment facilities. It emphasizes strategies such as rehydration therapy, water sanitation, hygien...e promotion, and vaccination to prevent the spread of cholera. The guide serves as a resource for healthcare professionals, logisticians, and public health officials to respond effectively to cholera outbreaks.
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