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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Diabetes in pregnancy

National Institute for Health and Care Excellence (NICE) National Institute for Health and Care Excellence (NICE) (2016) CC2

The document "Diabetes in Pregnancy" by NICE (National Institute for Health and Care Excellence) outlines quality standards for managing diabetes in women during pregnancy, with a focus on five key areas. First, it emphasizes the importance of preconception planning for women of childbearing age wit... more

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European Respiratory Society clinical practice guidelines for the diagnosis of asthma in children aged 5–16 years

Gaillard, E.A.; Kuehni, C.E.; Turner, S.; et al. European Respiratory Journal (2021) CC

Diagnosing asthma in children represents an important clinical challenge. There is no single gold-standard test to confirm the diagnosis. Consequently, over- and under-diagnosis of asthma is frequent in children. A task force supported by the European Respiratory Society has developed these evidence... more

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Compendium of Animal Rabies Prevention and Control, 2016

Brown C.M., Slavinski S., Ettestad P. et al National Association of State Public Health Veterinarians Compendium of Animal Rabies Prevention and Control Committee (2016) C2

Rabies is a fatal viral zoonosis and serious public health problem.1 All mammals are believed to be susceptible to the disease, and for the purposes of this document, use of the term animal refers to mammals. The disease is an acute, progressive encephalitis caused by viruses in the genus Lyssavirus... more

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Vectorial capacity of Aedes aegypti: effects of temperature and implications for global dengue epidemic potential

Jing Liu-Helmersson , H. Stenlund, A. Wilder-Smith, et al. PLOS One (2014) CC

Dengue is a mosquito-borne viral disease that occurs mainly in the tropics and subtropics but has a high potential to spread to new areas. Dengue infections are climate sensitive, so it is important to better understand how changing climate factors affect the potential for geographic spread and futu... more

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Serie «de la intención a la acción»: Reflexiones regionales. Análisis de las consultas regionales informales con personas que viven con enfermedades no transmisibles y trastornos mentales 2023

World Health Organization (WHO) World Health Organization (WHO) (2023) C_WHO

El presente informe incluye análisis de consultas informales en cinco de las regiones de la OMS: la Región de África, la Región de las Américas (donde se realizaron consultas separadas para el Caribe y América del Norte, y para América Latina), la Región de Asia Sudoriental, la Región de Eu... more

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Serie «de la intención a la acción»: Reflexiones regionales. Análisis de las consultas regionales informales con personas que viven con enfermedades no transmisibles y trastornos mentales

World Health Organisation (WHO) (2023) C_WHO

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Zika: the origin and spread of a mosquito-borne virus

Mary Kay Kindhauser, Tomas Allen, Veronika Frank, et al. World Health Organization (WHO) (2016) CC

Bulletin of the World Health Organization 2016. doi: http://dx.doi.org/10.2471/BLT.16.171082 Objective: To describe the temporal and geographical distribution of Zika virus infection, and associated neurological disorders, from 1947 to February 2016.

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Model disability survey (MDS): survey manual

World Health Organization (WHO) & The World Bank (WB) WHO (2017) CC

The World Health Organization's Model Disability Survey (MDS) Manual is a tool to help implement the MDS in countries and to improve the quality of the interview process. This manual is intended to provide practical information about the survey instruments and their use during interviews. This manua... more

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Complex Trauma Standardized Measures
recommended

The National Child Traumatic Stress Network (NCTSN) (2019) C2

Overview of available standardized measures of Complex Trauma on www.nctsn.org | Accessed online February 2019

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90 лет нигерной теории паркинсонизма

В.В. Юдина, Н.С. Макаров, Г.К. Юдина et al. Саратовский научно-медицинский журнал (2009) C1

Статья посвящена 90-летию с момента создания нигерной теории болезни Паркинсона известным саратов-ским ученым К. Н. третьяковым. http://www.ssmj.ru/system/files/200902_279_282.pdf

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Type 2 Diabetes - Are you at risk?

Diabetes.co.uk. the global diabetes community (2024) CC2

Poster Type 2 Diabetes - Are you at risk? does this sound like you? book an appointment with your GP

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Zika virus disease timeline

World Health Organization WHO (2016) C_WHO

A chronological map of the presence of Zika only in those countries for which there is evidence of indigenous transmission by mosquitos, excluding the many countries that have notified imported Zika infections.

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Understanding Type 2 Diabetes - Know the risk factors

Diabetes.co.uk. the global diabetes community (2024) CC2

People are diagnosed with diabetes every 3 minutes. If you think you’re at risk, speak to your doctor.

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Are you at risk of developing Type 2 Diabetes?

Diabetes.co.uk. the global diabetes community (2024) CC2

Poster - Are you at risk of developing Type 2 Diabetes?

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Radiation Patient Treatment: Algorithm

Radiation Emergency Assistance CenterTraining Site (REAC ORAU (2016) C1

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Ethiopia - Multi-Sectorial Cholera Elimination Plan 2022 - 2028

Government of Ethiopia (2023) CC

Cholera which disproportionally impacts poor countries and the most vulnerable continues to affect at least 47 countries across the globe, resulting in an estimated 1.3 – 4 million cases, and 21,000 - 143,000 deaths per year worldwide. In Ethiopia, despite major improvements seen in the increasing... more