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CH 5: Effective strategies for detecting maltreatment of children and youth within the context of mental health and developmental assessment.

World Health Organization (2015) C_WHO
(New 2015) Scoping question: Within the context of mental health and developmental assessment of children and youth, what are the effective strategies for detecting maltreatment?
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CH 1: Caregiver skills training for the management of developmental disorders

World Health Organization (2015) C_WHO
(Updated 2015) Scoping question: What is the effectiveness of caregiver skills training in the management of children and adolescents with developmental disorders?
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Pharmacological interventions in adolescents with psychotic disorders
recommended

World Health Organization World Health Organization (2015) C_WHO
Q15. SCOPING QUESTION: Is pharmacological intervention effective and safe for treatment of psychotic disorders in adolescents (including schizophrenia and bipolar disorder)?
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Guidelines for the prevention, care and treatment of persons with chronic hepatitis B infection
recommended

World Health Organization (2015) C_WHO
The recommendations in these guidelines promote the use of simple, non-invasive diagnostic tests to assess the stage of liver disease and eligibility for treatment; prioritize treatment for those with most advanced liver disease and at greatest risk of mortality; and recommend the preferred use of n... more
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CH 3: Psychosocial interventions, treatment of emotional disorders.

World Health Organization (2015) C_WHO
[Updated 2015] Scoping question: What is the effectiveness of psychosocial interventions, including caregiver skills training, for emotional disorders in children and adolescents?
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CH 4: Antidepressants among adolescents with moderate-severe depressive disorder for whom psychosocial interventions have proven ineffective

World Health Organization (2015) C_WHO
(2015) Scoping question: Are antidepressants (specifically, tricyclic antidepressants and selective serotonin reuptake inhibitors) effective and safe in adolescents with moderate-severe depressive disorder for whom psychosocial interventions have proven ineffective?
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CH 2: Psychosocial interventions for treatment of behavioural disorders.

World Health Organization (2015) C_WHO
[Updated 2015] SCOPING QUESTION: What is the effectiveness of psychosocial interventions (including caregiver skills training) for behavioural disorders in children and adolescents?
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Community-Based Rehabilitation for People With Disabilities in Low- and Middle-income Countries: A Systematic Review

Iemmi, Valentina Gibson, Lorna Blanchet, Karl, et al. Campbell Collaboration (2015) CC
International Development vol. 11. DOI 10.4073/csr.2015.15
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WHO mhGAP Guideline update
recommended

WHO WHO (2015) C_WHO
Update of the Mental Health Gap Action Programme (mhGAP) Guideline for Mental, Neurological and Substance use Disorders May 2015
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Supervised dosing with a long acting opioid medication for the management of prescription opioid dependence (New 2015)

mhGAP; WHO (2015) C_WHO
SCOPING QUESTION: In the management of prescription opioid dependence, does supervised dosing with a long-acting opioid medication result in less opioid use and related harms than non-prescription, detoxification or usual care?
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Psychosocial interventions for the management of cannabis dependence [Updated 2015]

mhGAP; WHO (2015) C_WHO
SCOPING QUESTION: Which psychosocial interventions are effective in the management of cannabis dependence?
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Psychosocial interventions for the management of psychostimulant dependence (2015)

World Health Organization WHO mhGAP; WHO (2015) C_WHO
SCOPING QUESTION:Which psychosocial interventions are effective in the treatment of psychostimulant dependence for adults and young people?
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EPI 2: First-line anti-epileptic medication for management of acute convulsive seizures, when intravenous access is available [2015]

mhGAP; WHO (2015) C_WHO
SCOPING QUESTION: In adults with acute convulsive seizures, where intravenous access is available, which first-line anti- epileptic medication should be used to abort seizures when compared to comparator?
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EPI 5: Anti-epileptic medicines for medication resistant convulsive epilepsy. [New 2015]

mhGAP; WHO (2015) C_WHO
SCOPING QUESTION: For adults and children with medication-resistant convulsive epilepsy, which anti-epileptic medications produce benefits and/or harm in the specified outcomes when compared to a placebo or a comparator?
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EPI 4: Antiepileptic medications for adults and children with HIV

World Health Organization WHO (2015) C_WHO
Scoping Question: For adults and children living with HIV, which antiepileptic medications (such as phenobarbital, phenytoin, carbamazepine or valproic acid) produce benefits and/or harms when compared to a placebo or controls?
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EPI 1: Antiepileptic medications for management of acute convulsive seizures when no intravenous access is available

World Health Organization WHO (2015) C_WHO
[Updated 2015] Scoping Question: In adults with acute convulsive seizures in first-level care or in the community (when no IV access is available), which antiepileptic medications produce benefits and/or harm when compared to comparator?
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EPI 3: Anti-epileptic medications for management of established status epilepticus [Updated 2015]

mhGAP; WHO (2015) C_WHO
SCOPING QUESTION: In adults with established status epilepticus (i.e., seizures persisting after the first-line treatment with benzodiazepines [or benzodiazepines-resistant status epilepticus]), which anti-epileptic medications are associated with cessation of seizures and reduced adverse effects)? ... more
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Role of depot antipsychotic medication in long-term antipsychotic treatment

World Health Organization WHO (2015) C_WHO
Q5.SCOPING QUESTION: In individuals with psychotic disorders (including schizophrenia) who require long-term antipsychotic treatment, what is the safety and role of depot antipsychotic medication?
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Isoniazid preventive therapy for tuberculosis in South Africa: An assessment of the local evidence base

R Wood, L-G. Bekker (2014) CC
Review S Afr Med J 2014;104(3):174-177. DOI: 10.7196/SAMJ.7968
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Efficacy of isoniazid prophylactic therapy in prevention of tuberculosis in children: a meta–analysis

J. Ayieko, L. Abuogi, B. Simchowitz, et al. BMC Infectious Diseases (2014) CC
Research Article BMC Infectious Diseases 2014, 14:91/1471-2334/14/91