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Combination of two or more antipsychotic medications for psychotic disorders

World Health Organization WHO (2012) C_WHO
Q2: In individuals with psychotic disorders (including schizophrenia), is the use of two or more antipsychotic medications concurrently more effective and safer than the use of one antipsychotic only?
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Antipsychotic medications for psychotic disorders

World Health Organization WHO (2012) C_WHO
Q1: In individuals with psychotic disorders (including schizophrenia), are antipsychotic drugs safe and effective?
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Role of anticholinergic medications in patients requiring long-term antipsychotic treatment for psychotic disorders

World Health Organization WHO (2012) C_WHO
Q6: In individuals with psychotic disorders (including schizophrenia) who require long term antipsychotic treatment, are anticholinergic medications more effective in preventing or reducing extrapyramidal side-effects and/or improving treatment adherence than placebo/treatment as usual?
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Schizophrenia and other psychotic disorders of early onset

J. Starling; I. Feijo IACAPAP (2012) C2
Other disorders Chapter H.5
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Psychosis and bipolar disorders

World Health Organization WHO (2022) C_WHO
Evidence-based recommendations for management of psychosis and bipolar disorders in non-specialized health settings
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Duration of antipsychotic treatment in individuals with long term and-or recurrent psychotic disorders

World Health Organization WHO (2012) C_WHO
Q4: In individuals with long term and/or recurrent psychotic disorders (including schizophrenia), should individuals be maintained on pharmacotherapy indefinitely or withdrawn from treatment in order to allow for the best outcomes?
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Case Formulation in Young People with Post-Traumatic Stress Disorder and First-Episode Psychosis

Halpin, E., Kugathasan, V., Hulbert, C., Alvarez-Jimenez, M. & Bendall, S Journal of Clinical Medicine (2016) CC
Background: Evidence based treatment interventions for young people with first-episode psychosis (FEP) and trauma histories is lacking. Although case formulation (CF) has been widely regarded in cognitive behavioural therapy manuals as beneficial, there is limited empirical research examining how cl... more
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Pharmacological interventions in adolescents with psychotic disorders
recommended

World Health Organization World Health Organization (2015) C_WHO
Q15. SCOPING QUESTION: Is pharmacological intervention effective and safe for treatment of psychotic disorders in adolescents (including schizophrenia and bipolar disorder)?
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Second-generation antipsychotic medications for psychotic disorders (including schizophrenia)
recommended

World Health Organization WHO (2012) C_WHO
Q14. SCOPING QUESTION: In adults with psychotic disorders (including schizophrenia), what is the comparative effectiveness and safety of second-generation antipsychotic medications?
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Pharmacological treatment of mental disorders in primary health care

World Health Organization WHO (2009) CC
The manual contains basic principles of prescribing followed by chapters on medicines used in psychotic disorders; depressive disorders; bipolar disorders; generalised anxiety and sleep disorders; obsessive-compulsive disorders and panic attacks; and alcohol and opioid dependence
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The ICD-10 Classification of Mental and Behavioural Disorders: Clinical descriptions and diagnostic guidelines. F10 - F19 Mental and behavioural disorders due to psychoactive substance use

World Health Organization (WHO) (1992) C_WHO
This block contains a wide variety of disorders that differ in severity (from uncomplicated intoxication and harmful use to obvious psychotic disorders and dementia), but that are all attributable to the use of one or more psychoactive substances (which may or may not have been medically prescribed)
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Management of physical health conditions in adults with severe mental disorders
recommended

World Health Organization WHO (2018) C_WHO
The global burden of disease due to mental disorders continues to rise, especially in low- and middle-income countries (LMIC). In addition to causing a large proportion of morbidity, mental disorders – especially severe mental disorders (SMD) – are linked with poorer health outcomes and increase... more
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Psychoeducation, family interventions and cognitive-behavioural therapy

World Health Organization WHO (2012) C_WHO
Q10: In individuals with psychotic disorders (including schizophrenia) and bipolar disorders are psychoeducation, family interventions and cognitive-behavioural therapy feasible and effective?
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Role of depot antipsychotic medication in long-term antipsychotic treatment

World Health Organization WHO (2015) C_WHO
Q5.SCOPING QUESTION: In individuals with psychotic disorders (including schizophrenia) who require long-term antipsychotic treatment, what is the safety and role of depot antipsychotic medication?
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Recovery-oriented psychosocial strategies enhancing independent living and social skills (such as life skills and social skills training)

World Health Organization WHO (2015) C_WHO
Q11. SCOPING QUESTIONS: In people with psychotic disorders (including schizophrenia and bipolar disorder) are recovery-oriented psychosocial strategies enhancing independent living and social skills (such as life skills and social skills training) feasible and effective?
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Recovery-oriented strategies enhancing vocational and economic inclusion (such as supported employment)

World Health Organization WHO (2015) C_WHO
Q12. SCOPING QUESTION: In people with psychotic disorders, including schizophrenia and bipolar disorder, are recovery-oriented strategies enhancing vocational and economic inclusion (such as supported employment) feasible and effective?
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Public Health Aspects of Mental Health Among Migrants and Refugees: A Review of the Evidence on Mental Health Care for Refugees, Asylum Seekers and Irregular Migrants in the WHO European Region

Priebe, S.; D. Giacco, and Rawda El-Nagib. World Health Organization WHO; Regional Office Europe (2016) C_WHO
Health Evidence Network Synthesis Report, No. 47 The increasing number of refugees, asylum seekers and irregular migrants poses a challenge for mental health services in Europe. This review found that these groups are exposed to risk factors for mental disorders before, during and after migration. ... more
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The social and cultural aspects of mental health in African societies

Mary Amuyunzu-Nyamongo Commonwealth Health Partnerships (2013) C2
The World Health Organization (WHO) defines mental health as ‘a state of well-being in which the individual realizes his or her own abilities, can cope with the normal stresses of life, can work productively and fruitfully, and is able to make a contribution to his or her community’. Mental illn... more
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Antipsychotics and mood stabilizers (lithium, valproate, or carbamazepine) for maintenance treatment of bipolar disorder

World Health Organization WHO (2018) C_WHO
Q8. SCOPING QUESTION: In people with bipolar disorders who require maintenance treatment, are a) antipsychotics or b) mood stabilizers (lithium, valproate or carbamazepine) effective and safe?