The study on single-dose cholera vaccine in Zambia evaluates the effectiveness of using a single dose of the oral cholera vaccine (OCV) during a 2016 outbreak in Lusaka. Due to limited vaccine supply, authorities opted for a one-dose emergency campaign instead of the usual two-dose regimen. A matche...d case-control study was conducted to assess vaccine effectiveness, showing 88.9% short-term protection against cholera. The findings suggest that a single-dose approach can be an effective strategy in outbreak settings, especially when vaccine supplies are constrained. However, further research is needed to determine long-term immunity and effectiveness in young children.
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This is an update (third edition) of the BACPR Standards & Core Components and represents current evidence-based best practice and a pragmatic overview of the structure and function of Cardiovascular Prevention and Rehabilitation Programmes (CPRPs) in the UK. The previously described seven standards... have now been reduced to six but without sacrificing any of the key elements and with a greater emphasis placed on measurable clinical outcomes, audit and certification. Similarly, the second edition provided an overview of seven core components felt to be essential for the delivery of quality prevention and rehabilitation, and this too has been reduced to six. The interplay between cardio-protective therapies and medical risk factors is almost impossible to disentangle for the vast majority of patients and even if specific drug therapies are deployed exclusively for risk factor modulation, the indirect effect will also be cardio-protective. Thus, these have been combined into a single core component – medical risk management.
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The plan outlines emergency health, WASH and communications interventions to contain and prevent further spread of the outbreak in the 227 high risk districts, where suspected cholera cases were reported during the period October 2016 to May 2017. Health and WASH clusters will continually identify p...riority districts from at
high risk districts, by considering the number of caseload and attack rate. As of 15 May, 30 priority high risk districts (10 Governorates) that report over 100 or more suspected cholera cases have been identified.
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Le panorama du paludisme a profondement changé durant la dernière décénnie. Les financements ont augmenté, les outils permettant de sauver des vies ont été mis en œuvre à plus grande échelle, la charge du paludisme a diminué et un nombre grandissant de pays envisagent son élimination.
C...e cadre actualisé fait le point sur les outils, les activités et les stratégies nécessaires pour atteindre l'élimination du paludisme et empêcher la reprise de la transmission dans les pays, quelle que soit l'étape à laquelle ils se trouvent sur la route menant à l'élimination ou l’intensité de la transmission. Le cadre est destiné à servir de référence pour élaborer des plans stratégiques d’élimination du paludisme au niveau national et doit être adapté aux contextes locaux.
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The GTFCC Laboratory Support for Public Health Surveillance document provides guidelines on using DNA-based molecular techniques for identifying and monitoring Vibrio cholerae strains in cholera outbreaks. It highlights the importance of genetic sequencing for tracking transmission, detecting new va...riants, and improving outbreak response. The report explains methods like PCR testing, whole genome sequencing (WGS), and multiple loci VNTR analysis (MLVA), detailing their advantages and applications. It also outlines best practices for sample collection, storage, and transportation, emphasizing collaboration between national and international laboratories to enhance cholera surveillance and control efforts.
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On 19 August 2016, the former UN Secretary-General announced a new approach to cholera in Haiti, consisting of two tracks. Track 1 focuses on reducing cholera transmission, improving access to care, and addressing water, sanitation, and health system issues. Track 2 aims to provide material assistan...ce to those most affected by cholera. The Secretary-General urged Member States to show solidarity with Haiti by increasing contributions. The UN General Assembly, in resolution 71/161, recognized the UN's moral responsibility to cholera victims and called for support to eliminate cholera and address its victims' suffering. The Secretary-General was requested to provide an update on the progress of this approach.
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The WHO Cholera Rapid Diagnostic Test (RDT) Target Product Profile outlines the key requirements for developing improved cholera RDTs. It highlights the need for fast, accurate, and easy-to-use tests for early outbreak detection in resource-limited settings. The document sets desired and acceptable ...performance criteria, including high sensitivity and specificity, rapid results (under 15 minutes), and usability by non-laboratory personnel. The tests should be affordable, stable in extreme conditions, and require minimal training. The goal is to enhance cholera surveillance and outbreak response, ensuring quick containment and improved public health outcomes.
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The document focuses on household water treatment methods to ensure access to safe drinking water, particularly in areas with limited access to clean water sources. It highlights the importance of safe water, noting that contaminated water is a major cause of waterborne diseases such as diarrhea and... cholera. Treating water at the household level is emphasized as an effective way to reduce health risks.
The document outlines several treatment methods, including boiling, which kills most pathogens; chlorination, which disinfects water by adding chlorine; filtration, which removes dirt and certain microbes using simple or advanced filters; and solar disinfection (SODIS), which involves exposing water in clear plastic bottles to sunlight for several hours to kill microbes. Additionally, it stresses the importance of safe water storage, such as using clean and covered containers to prevent recontamination, and practicing good hygiene, including regular handwashing and maintaining cleanliness around water sources.
By promoting these methods, the document aims to raise awareness and provide practical solutions for improving water quality at the household level, thereby reducing the spread of diseases and enhancing public health.
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The document provides WHO guidelines on fluid management for children with severe acute malnutrition (SAM) and cholera. It outlines protocols for rehydration therapy, including oral rehydration solutions (ORS) and intravenous fluids for cases of severe dehydration or shock. The guidelines emphasize ...careful monitoring to avoid overhydration and highlight the use of zinc supplementation to reduce diarrhea severity and future episodes. It also discusses the integration of therapeutic feeding to support recovery. The document is a resource for healthcare workers managing vulnerable children in cholera outbreaks.
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The "Hygiene Awareness Manual" focuses on promoting improved hygiene practices within communities, emphasizing personal and household hygiene, water safety, and environmental health. It highlights the importance of handwashing, oral hygiene, and maintaining cleanliness of the skin and clothing as ke...y aspects of personal and family hygiene. Specific practices such as regular bathing and wearing clean clothes are also emphasized.
For household hygiene, the manual provides guidance on safe food preparation and storage, as well as keeping living spaces, kitchens, and latrines clean to prevent contamination. It also addresses water safety, emphasizing the need to store water in clean containers, treat it for safe consumption, and dispose of wastewater properly to avoid environmental contamination.
The manual underscores the significance of balanced nutrition and food safety, offering guidelines for cooking and preserving food to reduce health risks. It also delves into disease prevention, explaining the causes and transmission of waterborne and hygiene-related diseases, such as cholera and dysentery, and outlining effective methods to prevent them through proper sanitation and hygiene.
This comprehensive guide serves as a practical resource for community health workers and households, aiming to foster better hygiene practices, prevent diseases, and enhance overall health and well-being.
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The document presents a humanitarian snapshot from October 2017 highlighting the dire situation of children in Yemen. Over 11 million Yemeni children needed humanitarian assistance due to the conflict that began in March 2015. The report shows one child dying every 10 minutes from preventable causes..., with 386,000 suffering from severe acute malnutrition. The education system was near collapse with 2,531 schools damaged or repurposed, depriving 1.5 million children of education. More than 7,000 children had been killed or injured in the conflict, and child labor and early marriages were increasing as negative coping mechanisms. The report also notes that 55% of Yemen's 2.9 million displaced persons were children.
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The WHO Cholera Vaccine Position Paper (August 2017) highlights the importance of oral cholera vaccines (OCVs) as a key tool in outbreak response and prevention, alongside water, sanitation, and hygiene (WASH) measures. It recommends OCVs for high-risk populations, endemic areas, and humanitarian cr...ises, emphasizing their effectiveness in reducing cases and mortality. The paper discusses two types of OCVs (Dukoral®, Shanchol™, Euvichol®) and supports the WHO-managed vaccine stockpile for rapid deployment in cholera-prone regions.
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The National Integrated Comprehensive Cholera Prevention and Control Plan (2017-2022) outlines Uganda's strategy to reduce cholera cases and mortality by 50% by 2022. The plan focuses on improving access to clean water, sanitation, and hygiene (WASH), strengthening disease surveillance, enhancing ca...se management, and implementing oral cholera vaccination (OCV) in high-risk areas. It emphasizes multi-sectoral collaboration, involving government agencies, NGOs, and local communities to ensure a sustainable response. Key interventions include community engagement, improved health services, and better outbreak preparedness, aiming for long-term cholera elimination in Uganda.
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This poster, designed for children, shows they key times for handwashing and demonstrates how to properly wash hands
This article describes WHO's efforts to combat a cholera outbreak in South Sudan in July 2017. The organization received 500,000 doses of oral cholera vaccine (OCV) and was working with South Sudan's Ministry of Health to launch a vaccination campaign from July 28 to August 3, 2017. At the time, the... country had reported 17,785 cholera cases and 320 deaths since the outbreak began in June 2016. The vaccination campaign targeted four counties with high transmission rates: Tonj East, Kapoeta South, Kapoeta North, and Kapoeta East. South Sudan was implementing an integrated approach to control cholera, combining patient care, surveillance, social mobilization, water and sanitation improvements, and vaccination. The article notes that approximately 6 million people in South Sudan were facing starvation, with food insecurity and drought exacerbating the risk of cholera spread as people resorted to using contaminated water sources.
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The "Regional Action Plan 2017–2030: Towards a Malaria-Free South-East Asia Region" by the World Health Organization (WHO) outlines a strategic framework to eliminate malaria in the 11 countries of the WHO South-East Asia Region by 2030. It focuses on reducing transmission, particularly of Plasmod...ium falciparum and P. vivax, addressing multidrug resistance, improving surveillance, and ensuring universal access to diagnosis, treatment, and prevention. The plan sets clear objectives and milestones and emphasizes strong governance, cross-border collaboration, community involvement, and sustainable financing to achieve and maintain a malaria-free status across the region.
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Le Cadre stratégique de la communication pour le changement social et comportemental concernant le paludisme 2018–2030, élaboré par le Partenariat RBM, propose une approche coordonnée pour renforcer la communication dans la lutte contre le paludisme. Il vise à influencer positivement les comp...ortements individuels, communautaires et institutionnels à travers des stratégies adaptées aux contextes locaux. Le document met l’accent sur la participation communautaire, l’utilisation des données pour orienter les interventions, et la collaboration entre secteurs afin de soutenir les efforts mondiaux d’élimination du paludisme d’ici 2030.
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The document "Proteksyon Maladi" focuses on preventing waterborne and hygiene-related diseases through practical measures. It emphasizes the importance of personal hygiene, including washing hands with soap and clean water before eating, after using the toilet, and during food preparation. Maintaini...ng personal cleanliness is highlighted as a key step in preventing the spread of diseases.
Water safety is another critical focus, with recommendations to use treated or boiled water for drinking and cooking and to store water in clean, covered containers to prevent contamination. The document also addresses sanitation, encouraging the construction and maintenance of latrines to eliminate open defecation and promoting proper waste disposal to protect the environment and water sources.
Overall, the document serves as an educational resource, providing simple and effective strategies for communities to reduce the risk of diseases and improve public health through better hygiene, sanitation, and water safety practices.
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The document "J-esyon ak bon manipilasyon manje yo" focuses on proper food handling and hygiene practices to prevent contamination and foodborne illnesses. It provides comprehensive guidelines for individuals and communities, emphasizing the importance of food safety. Key recommendations include kee...ping raw and cooked foods separate, ensuring thorough cooking of perishable items like meat and fish, and checking canned goods for damage or expiration before use. It stresses the need to use treated or boiled water for cooking, drinking, and washing food, as contaminated water can lead to diseases such as diarrhea, typhoid, and skin infections.
The document also highlights critical hygiene practices, such as washing hands with soap and treated water before handling food or eating, and thoroughly cleaning food preparation areas. Proper storage of food at suitable temperatures to prevent spoilage is another key focus, along with protecting food from animals, insects, and other sources of contamination. Overall, the manual emphasizes that maintaining proper hygiene and safe food handling practices is vital for preventing illnesses and promoting public health, making it a valuable resource for educating communities on food safety.
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Fact sheet Cholera in Creole
The cholera factsheet provides key information on prevention, symptoms, and treatment. It emphasizes hygiene, safe food handling, and water treatment through boiling, filtering, or disinfection. Cholera, a severe diarrheal disease from contaminated water, causes dehydra...tion and can be fatal if untreated. Symptoms include watery diarrhea, vomiting, and weakness. Treatment focuses on rapid rehydration with oral rehydration solutions (ORS) and continued feeding. The guide also covers safe waste disposal, emergency latrines, and burial practices to prevent spread. It aims to educate communities on cholera prevention, early detection, and life-saving care.
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