This publication describes the reasons for the resurgence of malaria in Kyrgyzstan and presents an analysis of evidence-based elimination strategies and policies that were applied to contain the epidemic and outbreaks of the disease, achieve its elimination, and maintain the country malaria-free. The strong political commitment and the mobilization of human resources that were crucial in achieving elimination are emphasized. It is hoped that the experiences of Kyrgyzstan's national malaria control programme can assist other countries aiming to eliminate malaria. The publication is intended for health managers and personnel, researchers, teachers, students and post-graduates at medical schools.