Flussdiagramm zur Verdachtsfallabklärung
Any individual that meets the suspected case definition of monkeypox should be offered testing in appropriately equipped laboratories by staff trained in the relevant technical and safety procedures. Confirmation of monkeypox virus infection is based on nucleic acid amplification testing (NAAT), usi...ng real-time or conventional polymerase chain reaction (PCR), for detection of unique sequences of viral DNA. PCR can be used alone, or in combination with sequencing. The recommended specimen type for laboratory confirmation of monkeypox is skin lesion material, including swabs of lesion surface and/or exudate, roofs from more than one lesion, or lesion crusts.
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Fact Sheet about Monkeypox
in English, Arabic, Russian, French, Spanish, Chinese
Cases of human monkeypox are rarely seen outside of west and central Africa. There are few data regarding viral kinetics or the duration of viral shedding and no licensed treatments. Two oral drugs, brincidofovir and tecovirimat, have been approved for treatment of smallpox and have demonstrated eff...icacy against monkeypox in animals. Our aim was to describe the longitudinal clinical course of monkeypox in a high-income setting, coupled with viral dynamics, and any adverse events related to novel antiviral therapies.
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Therapiehinweise des STAKOB unter Mitwirkung von BfArM, DGI, DGPI, DTG, PEI und Pocken Konsiliarlabor RKI - ZBS 1
Where are the outbreaks? What is monkeypox? Recongnizing monkeypox and more. An update on the monkeypox outbreak including protection, diagnosis, treatment.
Nach dem derzeitigen Informationsstand sind aktuell humane Infektionen durch das Affenpockenvirus (monkeypox virus, MPX) in einigen Regionen der Welt einschließlich mehreren europäischen Ländern aufgetreten. Die Daten belegen eine Mensch-zu-Mensch-Übertragung unter bestimmten Bedingungen. Die Ü...bertragung von MPX von Mensch zu Mensch erfolgt in der Regel durch engen Haut- bzw. Schleimhautkontakt mit infektiösem Material aus den Hautläsionen einer infizierten Person, sowie – seltener – durch respiratorische Tröpfchen/Sekrete z.B. bei längerem Kontakt von Angesicht zu Angesicht oder durch kontaminierte Gegenstände und Oberflächen. Bei diesem Erreger ist besonders zu beachten, dass Partikel des Affenpockenvirus eingebettet in Sekreten bzw. getrocknet an Hautschuppen bzw. Schorfpartikeln für längere Zeiträume infektiös sein können, was eine sorgfältige und umfassende Reinigung und Desinfektion der Patientenumgebung bzw. der Oberflächen notwendig macht.
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Monkeypox: Cumulative confirmed cases, by date of confirmation
We have created a special Toolbox on Tuberculosis (TB), please click here to see all guidelines, manuals, reports & studies
Las recomendaciones contenidas en este módulo son un componente de las directrices unificadas de la OMS sobre la tuberculosis (TB) y están destinadas principalmente para el uso de los programas nacionales de control de la tuberculosis, los organismos de salud pública y otros interesados clave que... participan en la planificación, ejecución y seguimiento de las actividades de gestión programática de la TB farmacorresistente. El objetivo esta actualización es proporcionar información basada en la evidencia sobre determinadas áreas críticas que ayude a fundamentar el uso de nuevos esquemas totalmente orales y la posible ampliación de la ficha técnica de los nuevos medicamentos contra la TB. Los interesados directos podrán distinguir entre las recomendaciones anteriores que siguen siendo válidas, las que se han actualizado y las que se han elaborado recientemente sobre la base de estudios adicionales, teniendo en cuenta la gama de beneficios conocidos y posibles daños, los ejercicios de modelización y otros datos para fundamentar el proceso de toma de decisiones.
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This document provides guidance on interventions to prevent vaccine-preventable disease outbreaks in the context of mass population movement resulting from the ongoing crisis in Ukraine.
Supplement to: Guidance on vaccination and prevention of vaccine-preventable disease outbreaks for countries hosting refugees from Ukraine, April 2022 update
This document provides: • information on how to obtain vaccination documentation remotely (intended for refugees from Ukraine and intern...ally displaced persons (IDPs) in Ukraine who lack documentation of vaccination status for themselves or their children); • information on the types of vaccination documentation issued in Ukraine, and English translations of standard documents (intended for health care providers in refugee-host countries to facilitate assessment of vaccination status of refugees).
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Weekly Epidemiological Record No 9, 2022, 97, 61–80
This position paper supersedes the 2016 publication, “Malaria vaccine: WHO position paper-2016.”1 It includes the updated WHO recommendations on the wider use of the RTS,S/AS01 vaccine for the reduction of malaria morbidity and mortality in ...children living in areas of moderate to high malaria transmission. It also incorporates findings from the evaluation of the WHO-coordinated Malaria Vaccine Implementation Programme (MVIP), recommended by SAGE and MPAG in 2015, and from additional studies since 2015.
This paper does not include findings on vaccine efficacy in infants first vaccinated at 6–12 weeks of age. Because of the lower vaccine efficacy observed in this age category, WHO did not recommend pilot implementation or RTS,S/AS01 vaccine introduction for these young infants. Recommendations2 on the use of RTS,S/AS01 vaccine were discussed by SAGE and MPAG during a joint session in October 2021; evidence presented at the meeting can be accessed at https://terrance.who.int/mediacentre/data/ sage/SAGE_eYB_Oct2021.pdf
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