EXPERT OPINION ON DRUG SAFETY 2018, VOL. 17, NO. 11, 1129–1144.
Malaria during and after pregnancy contributes significantly to maternal mortality and adverse fetal outcomes. While effective and safe antimalarial treatments are essential, quinine — an older, less effective drug — has long bee...n favoured due to the limited safety data available on newer drugs. This review summarises the results of human studies investigating the safety and efficacy of antimalarial drugs during pregnancy and lactation.
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Int. J. Transl. Med. 2023, 3(2), 187-202; https://doi.org/10.3390/jtm3020014 .
Malaria and HIV are geographically in the tropics and subtropics of the world, including sub-Saharan Africa. Understanding the overlapping effect of both infections, especially among pregnant women, is crucial in managin...g pregnant women during antenatal care visits, and postpartum babies. It was realized that the prevalence of malaria among HIV-positive pregnant women ranges between 31–61%, while for non-HIV infected pregnant women the prevalence still stands between 10 and 36%. Co-infection is between 0.52 and 56.3%.
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The webinars aim to create awareness and convene discussion, bringing together Malaria Consortium technical experts and programmes teams with other actors working on the effective delivery of national and global health interventions worldwide.
Malaria Journal (2024) 23:255. Seasonal malaria chemoprevention (SMC) is a World Health Organization-recommended intervention for the prevention of malaria among children at high risk in areas with seasonal transmission. During the coronavirus disease 2019 (COVID-19) pandemic, SMC drug distribution ...was rapidly adapted to reduce contact and mitigate the risk of transmission between communities and community distributors, with caregivers administering doses.
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Since the 1960s, the Tanzanian government has been striving to improve access to quality healthcare, including primary care. However, tuberculosis (TB) remains a significant public health concern, with an estimated prevalence rate of 528 cases per 100,000 people. However, currently, only 36% of TB c...ases are detected, leaving many undiagnosed within the community. Challenges include low community awareness, long distances to diagnostic centres and delayed health-seeking behaviour.
To address these issues, the Ministry of Health (MOHCDGEC) adopted the ENGAGE TB approach, involving NGOs, civil society organisations (CSOs) and other non-state actors in community-based TB activities. This has increased the number of active organisations from five to approximately twenty.
Building on this success, the Ministry has developed national operational guidelines for community-based TB, TB/HIV and drug-resistant TB interventions, with the aim of improving collaboration between communities and health facilities. These guidelines will be updated regularly, and stakeholders are urged to comply fully with them and support TB control efforts.
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This table summarises the drugs used for malaria prevention, including adult and paediatric dosages, timing and special considerations. The medications listed are atovaquone/proguanil, chloroquine, doxycycline, hydroxychloroquine, mefloquine, primaquine and tafenoquine. The guidance covers the use o...f these drugs for primary and terminal prophylaxis, as well as contraindications (e.g. G6PD deficiency, pregnancy, and psychiatric or cardiac conditions) and safety precautions for children and special populations. The aim is to help travellers and healthcare providers reduce the risk of malaria during travel.
Accessed on 27/08/2025.
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En 2024, le Cap-Vert et l’Égypte ont été certifiés exempts de paludisme, ce qui prouve qu'il est possible d'éliminer la maladie avec une volonté politique et des ressources adaptées. Cependant, en Afrique, où se concentrent 95 % des cas mondiaux et 97 % des décès (en 2023), les progrès ...stagnent et l’objectif d’élimination d’ici 2030 est menacé. Les principaux obstacles sont le déficit de financement, la résistance aux insecticides et aux médicaments, l'expansion du moustique Anopheles stephensi, le changement climatique, les crises humanitaires et la croissance démographique. Pour inverser la tendance, l’Afrique doit accélérer le déploiement de nouveaux outils (moustiquaires de nouvelle génération, vaccins), renforcer la mobilisation des ressources nationales et diversifier les financements. Une feuille de route de l’Union africaine vise à transformer ces engagements en actions concrètes pour éliminer le paludisme et ses conséquences sanitaires et économiques.
Accessed 27/08/2025.
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Реабилитационный потенциал социально-психологического сопровождения семей с проблемами химической зависимости предлагается рассматривать как ресурс преодолен...ия аддикций Актуальность исследования обусловле- на необходимостью разработки базового подхода — научно-доказательно- го обоснования организации психологической помощи семье с проблемой алкогольной и/или наркотической зависимости
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This integrated operational framework provides an overview of the connections between mental health, neurological and substance use (MNS) conditions, and their links to health, well-being and the broader public health and sustainable development agenda. The need for integrated approaches is increasi...ngly recognized as critical to address the complex interactions between mental health, brain health, substance use, and physical health, particularly in light of global threats such as the COVID-19 pandemic. The framework also provides a series of actions for governments and health service planners and advisors to achieve integration across four domains: leadership and governance; care services; promotion and prevention; and health information systems, evidence generation and research.
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The document is a summary report by the World Health Organization (WHO) Regional Office for the Eastern Mediterranean, focusing on a capacity-building workshop held in Abu Dhabi in 2019. The workshop addressed the management and care of substance use disorders, aiming to improve technical and manage...rial capacities in areas such as policy development, treatment services, prevention, monitoring, and international collaboration. Participants included representatives from 12 countries, WHO collaborating centers, and other UN agencies.
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The Global status report on alcohol and health and treatment of substance use disorders presents a comprehensive overview of alcohol consumption, alcohol-related harm and policy responses as well as treatment capacities for alcohol and drug use disorders worldwide. The report is based on data collec...ted by WHO from Member States and organized in accordance with the Sustainable Development Goals health target 3.5 which calls on countries to strengthen “the prevention and treatment of substance abuse, including narcotic drug abuse and harmful use of alcohol”. The chapter on alcohol and health continues the series of WHO global status reports on alcohol and health and presents the latest available data on the status of, and trends in, alcohol consumption, as well as estimates of the alcohol-attributable disease burden and descriptions of policy responses worldwide. On the basis of data collected from countries on the treatment of substance use disorders the report describes the status of key components of treatment responses to alcohol and drug use disorders and proposes a new service capacity index for these disorders as an additional contextual indicator for monitoring progress in this domain of SDG health target 3.5. The report concludes with broad directions for international action to accelerate progress towards achievement of SDG health target 3.5.
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Just under 2.5 million people die annually due to alcohol use. This global estimate, however, excludes most of the health burden
borne by others than the alcohol user. Alcohol’s harm to others includes a multitude of conditions, such as trauma from traffic crashes, fetal disorders due to prenatal... exposure to alcohol, as well as interpersonal and intimate partner violence. While alcohol’s causal role in these conditions is well-established, alcohol’s harm to others’ contribution to the overall health burden of alcohol remains unknown. This knowledge gap leads to a situation in which alcohol policy and prevention strategies largely focus on the reduction of alcohol’s detrimental health harms on the alcohol users, neglecting affected others and population groups most vulnerable to these harms, including women and children. In this article, we seek to elucidate why estimates for alcohol’s harm to others are lacking and offer guidance for future research. We also argue that a full assessment of the alcohol health burden that includes the harm caused by others’ alcohol use would enhance the visibility and public awareness of such harms, and advancing the evaluation of policy interventions to mitigate them.
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Было выявлено несколько ключевых факторов риска неинфекционных заболеваний (НИЗ), включая вредное употребление алкоголя. Алкоголь употребляет половина населения... Земли, а вредное употребление алкоголя является третьей по значимости причиной нездоровья и преждевременной смерти в мире
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Это учебное пособие содержит информацию о том, как спланировать обучение и содействовать работникам первичного звена медико-санитарной помощи с тем, чтобы они мог...ли уверенно проводить СКПК по вопросам употребления алкоголя среди своих пациентов. В пособии излагаются исходная информация и данные научных исследований, положенные в основу СКПК, и даются практические рекомендации по созданию программы внедрения, а также подробные учебные материалы для развития знаний и навыков участников организованных учебных занятий.
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Злоупотребление алкоголем и алкоголизм относятся к ведущим причинам ухудшения здоровья и повышения смертности населения. Чрезмерное употребление алкоголя служи...т третьей ведущей причиной глобального бремени болезней и относится к ведущим факторам уменьшения продолжительности жизни и повышения смертности населения. Злоупотребление алкоголем снижает трудоспособность и производительность труда, требует повышенных расходов на лечение расстройств, вызванных алкоголем, что влечет за собой серьезные экономические потери. Неблагоприятные медицинские и социальные последствия неумеренного употребления алкоголя определяют значимость эффективного лечения алкоголизма
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The Youth.gov webpage on "Substance Use/Misuse" provides information and resources about preventing and addressing substance abuse among youth. It highlights risk factors, prevention strategies, and support programs designed to reduce substance use and its negative impacts on young people. The site ...is part of a federal initiative to promote healthy and safe youth development.
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This guideline includes 48 updated and new evidence-based recommendations related to MNS conditions. The guideline is targeted towards non-specialized health workers at primary- or secondary-level healthcare facilities, or those working at the district level including basic inpatient and outpatient ...services.
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Demographic and socioeconomic data Progress towards HIV testing and treatment cascade targets by 2025 (2023) Health sector cascade (2023) Estimated number of people newly infected with HIV
In November 2022, WHO launched a strategy to address antimalarial drug resistance in Africa, emphasizing the need for stronger surveillance. While regional monitoring networks have been active in other regions, most in Africa have not convened since 2017–2018. To renew collaboration, WHO organized... a meeting bringing together countries from the African and Eastern Mediterranean regions. Participants shared recent data on antimalarial efficacy and resistance. While artemisinin-based combination therapies remain highly effective, some sites in Uganda and the United Republic of Tanzania reported lower-than-expected efficacy of artemether–lumefantrine. Delayed parasite clearance linked to Plasmodium falciparum Kelch-13 mutations was noted in Eritrea, Rwanda, Uganda and the United Republic of Tanzania. Discussions highlighted challenges in therapeutic efficacy studies, molecular marker surveillance and the need for improved genotyping to distinguish relapses from new infections.
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Проблема пьянства и алкоголизма продолжает оставаться одной из актуальных проблем общественного здоровья и здравоохранения и все чаще рассматривается в рамках д...емографической безопасности Республики Беларусь.
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