This document provides Technical content on ZIKV, its manifestations, complications, modes of transmission, and prevention measures to be used in answering frequently asked questions and conveying messages in information and communication materials, community talks, press conferences, etc.
Lancet Glob Health. 2016 Feb 1. pii: S2214-109X(16)00048-6. doi: 10.1016/S2214-109X(16)00048-6. [Epub ahead of print] Open Acess
ACAPS Briefing Note: Zika virus epidemic
These interim case definitions have been developed for the purpose of providing global standardization for classification and reporting of Zika virus cases. WHO guidance for the surveillance of Zika virus disease is currently being developed.
WHO will periodically review these interim case definiti...ons and update them as new information becomes available
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PLoS Negl Trop Dis 10(3): e0004530 -Published: March 2, 2016
This paper reviews the status of the Zika virus outbreak, including medical countermeasureoptions, with a focus on how the epidemiology, insect vectors, neuropathology, virology and immunology inform options and strategies available for m...edical countermeasure development and deployment.
Please download directly from the website Open Access: http://journals.plos.org/plosntds/article/asset?id=10.1371%2Fjournal.pntd.0004530.PDF
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This article was published on March 4, 2016, at NEJM.org.
DOI: 10.1056/NEJMoa1602412
Please download from the website: http://www.nejm.org/doi/full/10.1056/NEJMoa1602412
N Engl J Med. 2016 Jan 13. [Epub ahead of print] Free full text
The explosive pandemic of Zika virus infection occurring throughout South America, Central America, and the Caribbean (see map) and potentially threatening the United States is the most recent of four unexpected arrivals of important a...rthropod-borne viral diseases in the Western Hemisphere over the past 20 years. It follows dengue, which entered this hemisphere stealthily over decades and then more aggressively in the 1990s; West Nile virus, which emerged in 1999; and chikungunya, which emerged in 2013. Are the successive migrations of these viruses unrelated, or do they reflect important new patterns of disease emergence?
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A chronological map of the presence of Zika only in those countries for which there is evidence of indigenous transmission by mosquitos, excluding the many countries that have notified imported Zika infections.
In view of the global concern overthe outbreak of the Zika virus, both Elsevier and The Lancet have created a Zika Virus Resource Center on Elsevier Connect with the latest updates, research, reviews, editorials, correspondence and comentary to help healthcare professionals, medical researchers
and... the public understand the outbreak. Both info centers are advised by clinicians and professional editors and will be updated with the most current research and evidence-based information available
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The objective of this document is to guide the preparation and implementation of national preparedness plans for the safety of substances of human origin during outbreaks of Zika virus infection, both in affected and non-affected areas.
published online April 13, 2016, DOI: 10.1056/NEJMsr1604338. Please download directly from the webpage: http://www.nejm.org/doi/pdf/10.1056/NEJMsr1604338
Review article published online March 30, 2016, DOI: 10.1056/NEJMra1602113. Please download directly from the webpage: http://www.nejm.org/doi/pdf/10.1056/NEJMra1602113