This document outlines the best practices for mosquito control and surveillance in United Nations duty stations affected by mosquito-borne diseases. It sets out an integrated vector management (IVM) approach combining environmental, biological, mechanical, chemical and personal protection strategies to reduce mosquito populations and the transmission of diseases. Key elements include targeted control of larval and adult mosquitoes, the proper use of insecticides, community engagement, and ongoing surveillance. Particular emphasis is placed on eliminating breeding sites, responsibly applying larvicides and adulticides, and monitoring the effectiveness of interventions. The guide stresses the importance of implementing a comprehensive, well-monitored mosquito control programme that is tailored to local conditions.